Dmel\P{GAL4-Hsp70.PB}l(3)Eq1^Eq1 Insertion

General Information
Symbol	Dmel\P{GAL4-Hsp70.PB}l(3)Eq1^Eq1	Species	D. melanogaster
Name		FlyBase ID	FBti0018460
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GAL4-Hsp70.PB}	Expression data	GAL4 reporter/driver
Affected gene(s)	CG10660, l(3)Eq1, Scer\GAL4, w	Viability / fertility
Causes allele(s)	l(3)Eq1^Eq1, Scer\GAL4^Eq1, w^Eq1	Stock availability	1 publicly available
LINE ID
Genomic Location
Chromosomal location	3L ( 69C2-69C3 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
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FB2013_03	New/Merged/Split Record This record was either newly added to FlyBase for this release or is the result of merging or splitting existing records in this release
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	69C2-69C3 ( near gene of known cytology )
Cytological location (reported)	69C2 (reported as inferred from sequence location) (Tang and Sun, 2002) 69C2 (in situ hybridization reported) (Tang and Sun, 2002)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GAL4-Hsp70.PB}
Location-dependent role
Size
Associated alleles	Scer\GAL4^hs.PB w^+mC
Molecular map
Affected Gene(s)
Insertion may affect gene	CG10660 (Tang and Sun, 2002) l(3)Eq1 (Tang and Sun, 2002) Scer\GAL4 (Patel et al., 2009, Pi et al., 2001, Tang and Sun, 2002, Ou et al., 2002, Jafar-Nejad et al., 2003, Ahmed et al., 2003, Pi et al., 2004, Chandra et al., 2003, Jafar-Nejad et al., 2006, Acar et al., 2006, Zhang et al., 2007, Duan et al., 2011, Zhai et al., 2012, Xie et al., 2012, Tsai and Sun, 2004, Zhang et al., 2006, Yeh et al., 2010) w (Tang and Sun, 2002)
Alleles and Phenotypes
Causes alleles	l(3)Eq1^Eq1 (Tang and Sun, 2002) Scer\GAL4^Eq1 (Pi et al., 2001, Tang and Sun, 2002, Ou et al., 2002, Jafar-Nejad et al., 2003, Patel et al., 2009, Ahmed et al., 2003, Pi et al., 2004, Chandra et al., 2003, Jafar-Nejad et al., 2006, Acar et al., 2006, Zhang et al., 2007, Duan et al., 2011, Zhai et al., 2012, Xie et al., 2012, Tsai and Sun, 2004, Zhang et al., 2006, Yeh et al., 2010) w^Eq1 (Tang and Sun, 2002)

Lethality References lethal \| recessive (Tang and Sun, 2002)
Sterility References
Phenotype Manifest In
	pigment cell (Tang and Sun, 2002)
Detailed Description
Statement Reference Eye pigment distribution: equatorial. (Tang and Sun, 2002)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference third instar larval stage mesothoracic tergum \| presumptive (Tang and Sun, 2002) mesothoracic tergum \| presumptive & restricted (Ahmed et al., 2003, Jafar-Nejad et al., 2003) eye equator \| presumptive (Ou et al., 2002, Tang and Sun, 2002) eye disc \| restricted (Ou et al., 2002, Tang and Sun, 2002) arista \| presumptive (Tang and Sun, 2002) wing disc \| restricted (Ahmed et al., 2003, Tang and Sun, 2002, Jafar-Nejad et al., 2003) antennal disc \| restricted (Tang and Sun, 2002) antennal disc (Tang and Sun, 2002) prepupal stage P3 wing disc \| restricted (Pi et al., 2001) Comment:reference states 3 hr APF prepupal stage P4 mesothoracic tergum primordium (Pi et al., 2001) Comment:7 hr APF
Additional Information
Statement Reference Expression is observed in the anterior region of the presumptive notum in the dorsal mesothoracic disc. (Ahmed et al., 2003) Expression is observed in the anterior region of the presumptive notum in the dorsal mesothoracic disc, and is stronger at the anterior midline. (Chandra et al., 2003) Expression is observed in the anterior of the presumptive notum in the dorsal mesothoracic disc. (Jafar-Nejad et al., 2003) Late third instar expression is observed in the equator region of the eye disc. (Ou et al., 2002) The imaginal disc expression pattern is similar to that of eyg. (Tang and Sun, 2002) Expression is observed anterior of the presumptive notum in the dorsal mesothoracic disc during early stages of pupariation, and in the presumptive notum at later stages. (Pi et al., 2001)

Marker for	eye disc (Ou et al., 2002) eye equator \| presumptive (Tang and Sun, 2002) mesothoracic tergum \| presumptive (Ahmed et al., 2003, Jafar-Nejad et al., 2003)
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	43659 w^*; P{GAL4-Hsp70.PB}l(3)Eq1^Eq1/TM6B, Tb¹
Linkouts
Comments
	P{GAL4-Hsp70.PB}l(3)Eq1^Eq1 maps 197bp upstream of CG10660. The P{GawB} element is inserted such that the direction of transcription of the Scer\GAL4 and w genes in the element is opposite to the direction of transcription of CG10660. (Tang and Sun, 2002)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	Eg-GAL4 (Jafar-Nejad et al., 2006) Eq1 (Tang and Sun, 2002) Eq-GAL4 (Pi et al., 2004, Jafar-Nejad et al., 2003, Ahmed et al., 2003, Chandra et al., 2003, Pi et al., 2001, Ou et al., 2002, Zhang et al., 2007, Tsai and Sun, 2004, Yeh et al., 2010) eq-GAL4 (Ou et al., 2002, Patel et al., 2009) Eq-Gal4 (Acar et al., 2006, Xie et al., 2012) eq-Gal4 (Zhai et al., 2012, Zhang et al., 2006) Eq-gal4 (Duan et al., 2011) P{GAL4}Eq (Pi et al., 2001, FlyBase, 1992-) P{GAL4-Hsp70.PB}l(3)Eq1^Eq1 (Tang and Sun, 2002, FlyBase, 1992-)
Secondary FlyBase IDs

References ( 18 )
Research paper	Xie et al., 2012, PLoS ONE 7(4): e36362 Uif, a Large Transmembrane Protein with EGF-Like Repeats, Can Antagonize Notch Signaling in Drosophila. [FBrf0218242] Zhai et al., 2012, PLoS Genet. 8(3): e1002582 Antagonistic regulation of apoptosis and differentiation by the cut transcription factor represents a tumor-suppressing mechanism in Drosophila. [FBrf0217859] Duan et al., 2011, EMBO J. 30(15): 3120--3133 Insensitive is a corepressor for Suppressor of Hairless and regulates Notch signalling during neural development. [FBrf0214638] Yeh et al., 2010, Biochem. Biophys. Res. Commun. 391(1): 510--516 Drosophila notal bristle as a novel assessment tool for pathogenic study of Tau toxicity and screening of therapeutic compounds. [FBrf0209785] Patel et al., 2009, J. Cell Biol. 185(7): 1181--1194 The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy. [FBrf0208174] Acar et al., 2006, Development 133(10): 1979--1989 Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator. [FBrf0190268] Jafar-Nejad et al., 2006, Development 133(9): 1683--1692 Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin. [FBrf0190299] Zhang et al., 2006, Dev. Cell 10(6): 719--729 A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. [FBrf0194555] Pi et al., 2004, Proc. Natl. Acad. Sci. U.S.A. 101(22): 8378--8383 phyllopod is a target gene of proneural proteins in Drosophila external sensory organ development. [FBrf0179385] Tsai and Sun, 2004, genesis 39(2): 141--153 Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development. [FBrf0179489] Ahmed et al., 2003, Development 130(25): 6295--6304 echinoid mutants exhibit neurogenic phenotypes and show synergistic interactions with the Notch signaling pathway. [FBrf0167515] Chandra et al., 2003, Dev. Biol. 256(2): 302--316 The Drosophila IgC2 domain protein Friend-of-Echinoid, a paralogue of Echinoid, limits the number of sensory organ precursors in the wing disc and interacts with the Notch signaling pathway. [FBrf0158849] Jafar-Nejad et al., 2003, Genes Dev. 17(23): 2966--2978 Senseless acts as a binary switch during sensory organ precursor selection. [FBrf0167609] Ou et al., 2002, Genes Dev. 16(18): 2403--2414 Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development. [FBrf0152002] Tang and Sun, 2002, genesis 34(1-2): 39--45 Use of mini-white as a reporter gene to screen for GAL4 insertions with spatially restricted expression pattern in the developing eye in Drosophila. [FBrf0152374] Pi et al., 2001, Development 128(14): 2699--2710 A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny. [FBrf0138359]
Supplementary material	Zhang et al., 2007, Genetics 176(2): Supplement to Zhang et al., 2007. [FBrf0203184]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GAL4-Hsp70.PB}l(3)Eq1Eq1 Insertion

Dmel\P{GAL4-Hsp70.PB}l(3)Eq1^Eq1 Insertion