Dmel\P{lacW}Gp150^P8 Insertion

General Information
Symbol	Dmel\P{lacW}Gp150^P8	Species	D. melanogaster
Name		FlyBase ID	FBti0023838
Feature type	transposable_element_insertion_site	Created / Updated	2002-12-12/2002-12-12
Description
Inserted element	P{lacW}	Localized function
Affected gene(s)	Gp150	Expression data
Causes allele(s)	Gp150^P8	Viability / fertility
LINE ID		Stock availability
Genomic Location
Chromosomal location	2R ( 58D3 )	Sequence location
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	58D3 ( near gene of known cytology )
Cytological location (reported)
Chromosome in situ
Sequence Data
Flanking sequence
Inserted Element
Construct	P{lacW}
Location-dependent role
Size	10.691Kb
Associated alleles	w^+mC Ecol\lacZ^P\T.W
Molecular map
Transposon class
Element type
Affected Gene(s)
Insertion within gene
Insertion may affect gene	Gp150 (Melnattur et al., 2002)
Orientation (relative to gene)	Gene Orientation References
Alleles and Phenotypes
Causes alleles	Gp150^P8 (Melnattur et al., 2002, Fetchko et al., 2002)

Lethality References
Sterility References
Phenotype Manifest In
	ommatidium (Fetchko et al., 2002)
Detailed Description
Statement Reference The addition of N^55e11/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 42.3%. The addition of Dl^9P/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 67.6%. The addition of Dl^9P/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 44.6%. (Fetchko et al., 2002) 19.2% of ommatidia in Gp150^P8/Gp150^k11120b animals are mutant. (Fetchko et al., 2002)
Expression Data
Reporter Expression
Stage Tissue/Position Reference
Additional Information
Statement Reference

Assay mode
Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{lacW}Gp150^P8 (Melnattur et al., 2002, FlyBase, 1992-)
Secondary FlyBase IDs

References ( 5 )
Research paper	Li et al., 2003, Development 130(13): 2819--2827 Scabrous and Gp150 are endosomal proteins that regulate Notch activity. [FBrf0161465] Fetchko et al., 2002, EMBO J. 21(5): 1074--1083 Drosophila Gp150 is required for early ommatidial development through modulation of Notch signaling. [FBrf0144849] Melnattur et al., 2002, genesis 34(1-2): 29--33 P(52A-GAL4) is an insertion in the Drosophila gp150 gene. [FBrf0151713] Tian and Zinn, 1994, J. Biol. Chem. 269(45): 28478--28486 An adhesion molecule-like protein that interacts with and is a substrate for a Drosophila receptor-linked protein tyrosine phosphatase. [FBrf0076712]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]

Dmel\P{lacW}Gp150P8 Insertion

Dmel\P{lacW}Gp150^P8 Insertion