A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{SUPor-P}hppyKG05537 Insertion

General Information
Symbol Dmel\P{SUPor-P}hppyKG05537 Species D. melanogaster
Name FlyBase ID FBti0024509
Feature type transposable_element_insertion_site
Description
Inserted element P{SUPor-P} Expression data
Affected gene(s) hppy Viability / fertility viable, fertile
Causes allele(s) hppyKG05537 Stock availability 1 publicly available
LINE ID KG05537
Genomic Location
Chromosomal location 2R ( 56C1 ) Sequence location 2R:15,066,260..15,066,260 [+]
Map ( GBrowse ) detailed view FBti0011138 FBti0105701 FBti0055093 FBti0024509 FBti0107458 FBti0110964 FBti0071173 FBti0027967 FBti0025945 FBti0051600 FBti0064772 FBti0046494 FBti0048965
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Description
What does this section display?
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FB2012_01
FB2011_10
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Chromosome (arm)
Sequence Location
2R:15,066,260..15,066,260 [+]
(Gene Disruption Project members, 2001-)
Orientation
Cytological location
(computed by FlyBase)
56C1 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
56C1 (reported as inferred from sequence location)
(Gene Disruption Project members, 2001-)
Comments concerning
location
hide Sequence Data
Flanking sequence
BH854558
(Gene Disruption Project members, 2001-, FlyBase, 1992-)
hide Inserted Element
Construct P{SUPor-P}
Location-dependent
role
Size 11.467Kb
Associated alleles
gypsy\su(Hw)BR430
wBR.E.BR
y+mDint2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
hppy
(Corl et al., 2009, FlyBase Curators, 2008)
hide Alleles and Phenotypes
Causes alleles
hppyKG05537
(FlyBase Curators, 2008, Corl et al., 2009)
Lethality
References
viable
(Gene Disruption Project members, 2001-)
Sterility
References
fertile
(Gene Disruption Project members, 2001-)
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
Mutant flies show increased resistance to ethanol-induced sedation compared to control flies.
(Corl et al., 2009)
The increased sensitivity to ethanol-induced sedation caused by expression of Egfr[GD1654] under the control of Scer\GAL4[elav-C155] is completely suppressed by hppy[KG05537].
(Corl et al., 2009)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
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FlyView (LinkOut)
hide Data on Genetic Line
Line ID
KG05537
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
14443
y1 w67c23; P{SUPor-P}hppyKG05537
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hide Comments
Location 2R:14693618-14693619 confirmed by FlyBase alignment of dbGSS accession BH854558 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation revised.
(FlyBase, 2005)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
KG05537
(Gene Disruption Project members, 2001-)
P{SUPor-P}CG7097KG05537
 
P{SUPor-P}hppyKG05537
 
P{SUPor-P}KG05537
(FlyBase, 2005, FlyBase, 1992-)
Secondary FlyBase IDs
hide References ( 6 )
Research paper
Corl et al., 2009, Cell 137(5): 949--960
Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors. [FBrf0208186]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
FlyBase analysis
FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations.
Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]