Dmel\P{ry11}E(bx)^ry122 Insertion

General Information
Symbol	Dmel\P{ry11}E(bx)^ry122	Species	D. melanogaster
Name		FlyBase ID	FBti0025342
Feature type	transposable_element_insertion_site
Description
Inserted element	P{ry11}	Expression data
Affected gene(s)	E(bx)	Viability / fertility
Causes allele(s)	E(bx)^ry122	Stock availability	1 publicly available
LINE ID
Genomic Location
Chromosomal location	3L ( 61B2-61B3 )	Sequence location
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	61B2-61B3 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{ry11}
Location-dependent role
Size	8.403Kb
Associated alleles	ry^+t7.2
Molecular map
Affected Gene(s)
Insertion may affect gene	E(bx) (Badenhorst et al., 2002, Berg and Spradling, 1991)
Alleles and Phenotypes
Causes alleles	E(bx)^ry122 (Badenhorst et al., 2002, Berg and Spradling, 1991)

Lethality References lethal \| germline clone \| maternal effect (Badenhorst et al., 2002) lethal \| recessive (Berg and Spradling, 1991)
Sterility References
Phenotype Manifest In
	embryonic/larval hemocyte \| supernumerary (Ragab, 2006) melanotic mass (Badenhorst et al., 2002)
Detailed Description
Statement Reference E(bx)^ry122 mutants show class I dendrite branching defects at late larval stages. (Parrish et al., 2006) Df(2R)ED3921 fails to suppress the melanotic tumour and increased larval hemocyte number of E(bx)^ry122 mutants. (Ragab, 2006) E(bx)^ry122 mutants have a high incidence of melanotic tumours and an increased number of larval hemocytes. (Ragab, 2006) The frequency of abnormal dorsal appendages in embryos derived from females carrying EcR^{B1-ΔC655.F645A.Scer\UAS} under the control of Scer\GAL4^slbo.2.6 (23%) is increased if the females are also heterozygous for E(bx)^ry122 (84%). (Badenhorst et al., 2005) The male X chromosome in E(bx)^ry122/Df(3L)3643 mutants is highly aberrant. E(bx)^Nurf301-2/E(bx)^ry122 and E(bx)^ry122/E(bx)^Nurf301-3 mutant larvae exhibit melanotic tumours. (Badenhorst et al., 2002)
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	10628 P{ry11}E(bx)^ry122, mwh¹ ry⁵⁰⁶ e¹/TM3, ry^RK Sb¹ Ser¹
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{ry11}E(bx)^ry122 (Badenhorst et al., 2002, FlyBase, 1992-) P{ry11}l(3)122¹ (Berg and Spradling, 1991, FlyBase, 1992-) P{ry11}l(3)ry122¹ (FlyBase, 1992-) P{ry^+t7.2=ry11}l(3)122¹ (FlyBase, 1992-)
Secondary FlyBase IDs
	FBti0000904 FBti0004857
References ( 6 )
Research paper	Parrish et al., 2006, Genes Dev. 20(7): 820--835 Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. [FBrf0190556] Badenhorst et al., 2005, Genes Dev. 19(21): 2540--2545 The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis. [FBrf0190536] Badenhorst et al., 2002, Genes Dev. 16(24): 3186--3198 Biological functions of the ISWI chromatin remodeling complex NURF. [FBrf0155786] Berg and Spradling, 1991, Genetics 127: 515--524 Studies on the rate and site-specificity of P-element transposition. [FBrf0054167]
Supplementary material	Ragab, 2006, Genetics 172(2): Supplemental data. [FBrf0191785]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]

Dmel\P{ry11}E(bx)ry122 Insertion

Dmel\P{ry11}E(bx)^ry122 Insertion