A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{EPgy2}vps24EY04708 Insertion

General Information
Symbol Dmel\P{EPgy2}vps24EY04708 Species D. melanogaster
Name FlyBase ID FBti0027337
Feature type transposable_element_insertion_site
Description
Inserted element P{EPgy2} Expression data
Affected gene(s) vps24 Viability / fertility
Causes allele(s) vps24EY04708 Stock availability 1 publicly available
LINE ID EY04708
Genomic Location
Chromosomal location 3R ( 82A3 ) Sequence location 3R:136,645..136,645 [-]
Map ( GBrowse ) detailed view FBti0061710 FBti0061792 FBti0125885 FBti0069866 FBti0027337 FBti0040284 FBti0106978 FBti0048446 FBti0050666 FBti0041401 FBti0104977
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Description
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This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
3R:136,645..136,645 [-]
(Gene Disruption Project members, 2001-)
Orientation
Cytological location
(computed by FlyBase)
82A3 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
82A4 (reported as inferred from sequence location)
(Gene Disruption Project members, 2001-)
Comments concerning
location
hide Sequence Data
Flanking sequence
CC060356
(Gene Disruption Project members, 2001-, FlyBase, 1992-)
hide Inserted Element
Construct P{EPgy2}
Location-dependent
role
mobile activating element (UASG)
(Bellen et al., 2004)
Size 10.908Kb
Associated alleles
Scer\UAS14x.P\T
TrlBRcRa
w+mC
y+mDint2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
vps24
(Gene Disruption Project members, 2001-, Ahmad et al., 2009, FlyBase Curators, 2008)
hide Alleles and Phenotypes
Causes alleles
vps24EY04708
(Ahmad et al., 2009, FlyBase Curators, 2008)
Lethality
References
Sterility
References
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
A single copy of vps24[EY04708] does not cause an eye phenotype.
(Ahmad et al., 2009)
A single copy of vps24[EY04708] significantly enhances the Hsap\CHMP2B[Intron5.Scer\UAS] Scer\GAL4[GMR.PF] phenotype in 1-day-old flies.
(Ahmad et al., 2009)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
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FlyView (LinkOut)
hide Data on Genetic Line
Line ID
EY04708
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
15763
y1 w67c23; P{EPgy2}vps24EY04708/TM3, Sb1 Ser1
hide Linkouts
hide Comments
Location 3R:136644-136646 confirmed by FlyBase alignment of dbGSS accession CC060356 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation confirmed.
(FlyBase, 2005)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
EY04708
(Gene Disruption Project members, 2001-)
P{EPgy2}CG9779EY04708
(FlyBase, 1992-)
P{EPgy2}EY04708
(FlyBase, 2005, FlyBase, 1992-)
P{EPgy2}vps24EY04708
 
vps24EY04708
(Ahmad et al., 2009)
Secondary FlyBase IDs
hide References ( 6 )
Research paper
Ahmad et al., 2009, Proc. Natl. Acad. Sci. U.S.A. 106(29): 12168--12173
Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia. [FBrf0208495]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
FlyBase analysis
FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations.
Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]