Dmel\P{GawB}NP2631 Insertion

General Information
Symbol	Dmel\P{GawB}NP2631	Species	D. melanogaster
Name		FlyBase ID	FBti0034959
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4	Viability / fertility
Causes allele(s)	Scer\GAL4^NP2631	Stock availability	1 publicly available
LINE ID
Genomic Location
Chromosomal location	2R ( 44A3 )	Sequence location	2R:3,917,423..3,917,484 [+]
Map ( GBrowse )
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location	2R:3,917,423..3,917,484 [+] (FlyBase, 2005)
Orientation
Cytological location (computed by FlyBase)	44A3 ( inferred by FlyBase from sequence location )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence	AG216420 (FlyBase, 1992-)
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Pitman et al., 2011, Tanaka et al., 2008, Yu et al., 2010, Nfonsam et al., 2012, Pauls et al., 2010)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^NP2631 (Pitman et al., 2011, Tanaka et al., 2008, Yu et al., 2010, Nfonsam et al., 2012, Pauls et al., 2010)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference adult stage mushroom body anterior paired lateral cell (Tanaka et al., 2008, Pitman et al., 2011) adult protocerebrum \| subset (Tanaka et al., 2008) mushroom body alpha-lobe (Tanaka et al., 2008) mushroom body beta-lobe (Tanaka et al., 2008) adult pedunculus (Tanaka et al., 2008) calyx of adult mushroom body (Tanaka et al., 2008) mushroom body accessory calyx (Tanaka et al., 2008) neuron of median bundle (Pitman et al., 2011) neuron of protocerebral bridge (Pitman et al., 2011) subesophageal ganglion neuron (Pitman et al., 2011) adult mushroom body gamma-lobe (Tanaka et al., 2008) adult mushroom body beta'-lobe (Tanaka et al., 2008) adult mushroom body alpha'-lobe (Tanaka et al., 2008)
Additional Information
Statement Reference Scer\GAL4[NP2631] is expressed in a subset of neurons in the adult brain, including the median bundle, protocerebral bridge, subesophageal ganglion and the mushroom body anterior paired lateral cell. (Pitman et al., 2011)

Marker for
Reflects expression of
Reporter construct used in assay	Avic\GFP^{S65T.Scer\UAS} (Tanaka et al., 2008) Mmus\Cd8a^{Scer\UAS.T:Avic\GFP} (Pitman et al., 2011, Tanaka et al., 2008)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Kyoto	104266 w^*; P{GawB}NP2631 / CyO
Linkouts
Comments
	Location 2R:3541729-3541792 determined by FlyBase alignment of dbGSS accession AG216420 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation revised. (FlyBase, 2005)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	NP2631 (Pitman et al., 2011, Tanaka et al., 2008, Yu et al., 2010, Pauls et al., 2010) np2631-Gal4 (Nfonsam et al., 2012) P{GawB}NP2631 (FlyBase, 1992-, ) P{GawB}NP2631-5-1 (FlyBase, 2005, FlyBase, 1992-)
Secondary FlyBase IDs

References ( 8 )
Research paper	Nfonsam et al., 2012, PLoS ONE 7(8): e44583 Analysis of the Transcriptomes Downstream of Eyeless and the Hedgehog, Decapentaplegic and Notch Signaling Pathways in Drosophila melanogaster. [FBrf0219414] Pitman et al., 2011, Curr. Biol. 21(10): 855--861 A pair of inhibitory neurons are required to sustain labile memory in the Drosophila mushroom body. [FBrf0213725] Yu et al., 2010, Curr. Biol. 20(18): 1602--1614 Cellular Organization of the Neural Circuit that Drives Drosophila Courtship Behavior. [FBrf0211884] Tanaka et al., 2008, J. Comp. Neurol. 508(5): 711--755 Neuronal assemblies of the Drosophila mushroom body. [FBrf0205263] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Supplementary material	Pauls et al., 2010, J. Neurosci. 30(32): Supplemental Material. [FBrf0220210]
FlyBase analysis	FlyBase, 2005, Assessment of transgenic construct insertion sites. Assessment of transgenic construct insertion sites. [FBrf0184339] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]