Dmel\P{GawB}sqz^GAL4 Insertion

General Information
Symbol	Dmel\P{GawB}sqz^GAL4	Species	D. melanogaster
Name		FlyBase ID	FBti0037937
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4, sqz	Viability / fertility
Causes allele(s)	Scer\GAL4^sqz-GAL4, sqz^GAL4	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	3R ( 91F4 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	91F4 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Allan et al., 2003, Félix et al., 2007, Baumgardt et al., 2009, Losada-Pérez et al., 2010) sqz (Allan et al., 2003, Allan et al., 2003)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^sqz-GAL4 (Allan et al., 2003, Félix et al., 2007, Baumgardt et al., 2009, Losada-Pérez et al., 2010) sqz^GAL4 (Allan et al., 2003, Allan et al., 2003)

Lethality References lethal (Allan et al., 2003)
Sterility References
Phenotype Manifest In
	wing (Allan et al., 2003)
Detailed Description
Statement Reference Df(3R)Dl-KX23/sqz^GAL4 adults are immotile with a persistent tremor and die within 24 hours. 70% of adults also fail to inflate their wings. (Allan et al., 2003)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference embryonic stage 17 Tv neuron \| subset (Allan et al., 2003) distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference embryonic stage 15 -- 17 embryonic thorax \| restricted (Baumgardt et al., 2007) embryonic stage 15 -- larval stage Tvb neuron (Baumgardt et al., 2007) Tv neuron (Baumgardt et al., 2007)
Additional Information
Statement Reference Scer\GAL4[sqz-GAL4] is expressed in a subset of Tv neurons expressing both ap and Fmrf. (Allan et al., 2003)

Marker for
Reflects expression of
Reporter construct used in assay	Avic\GFP^{EGFP.nls.Scer\UAS.T:Hsap\MYC} (Baumgardt et al., 2007) Avic\GFP^{Scer\UAS.T:Mmmm\c-Ha-Ras,T:Hsap\MYC} (Baumgardt et al., 2007) Btau\MAPT^{Scer\UAS.T:Hsap\MYC} (Allan et al., 2003)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome
Replacement descendant of (target)	P{PZ}sqz⁰²¹⁰² (Allan et al., 2003)
Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{GAL4}sqz^GAL4 (Allan et al., 2003, FlyBase, 1992-) P{GawB}sqz^GAL4 (Allan et al., 2003, FlyBase, 1992-) sqz^Gal4 (Baumgardt et al., 2009) sqzGal4 (Félix et al., 2007) sqz-Gal4 (Losada-Pérez et al., 2010)
Secondary FlyBase IDs
	FBti0037953
References ( 8 )
Research paper	Losada-Pérez et al., 2010, Mech. Dev. 127(9-12): 458--471 Lineage-unrelated neurons generated in different temporal windows and expressing different combinatorial codes can converge in the activation of the same terminal differentiation gene. [FBrf0212045] Baumgardt et al., 2009, Cell 139(5): 969--982 Neuronal subtype specification within a lineage by opposing temporal feed-forward loops. [FBrf0209429] Baumgardt et al., 2007, PLoS Biol. 5(2): e37 Specification of neuronal identities by feedforward combinatorial coding. [FBrf0195184] Félix et al., 2007, Development 134(10): 1845--1852 Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development. [FBrf0200657] Allan et al., 2003, Cell 113(1): 73--86 Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code. [FBrf0158766] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Supplementary material	Allan et al., 2003, Cell 113(1): Supplementary material: tables S1 - S5. [FBrf0161463]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GawB}sqzGAL4 Insertion

Dmel\P{GawB}sqz^GAL4 Insertion