A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{EPgy2}capuEY12344 Insertion

General Information
Symbol Dmel\P{EPgy2}capuEY12344 Species D. melanogaster
Name FlyBase ID FBti0040275
Feature type transposable_element_insertion_site
Description
Inserted element P{EPgy2} Expression data
Affected gene(s) capu Viability / fertility fertile, viable
Causes allele(s) capuEY12344 Stock availability 1 publicly available
LINE ID EY12344
Genomic Location
Chromosomal location 2L ( 24C8 ) Sequence location 2L:3,884,414..3,884,414 [+]
Map ( GBrowse ) detailed view FBti0124550_2 FBti0124550_1 FBti0042104 FBti0057836 FBti0040275 FBti0044447 FBti0046829 FBti0048722 FBti0109953 FBti0057167 FBti0055725 FBti0070450 FBti0124551_2 FBti0124551_1
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Description
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
2L:3,884,414..3,884,414 [+]
(Gene Disruption Project members, 2001-)
Orientation
Cytological location
(computed by FlyBase)
24C8 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
24C8 (reported as inferred from sequence location)
(Gene Disruption Project members, 2001-)
Comments concerning
location
hide Sequence Data
Flanking sequence
CL844496
(Gene Disruption Project members, 2001-)
hide Inserted Element
Construct P{EPgy2}
Location-dependent
role
mobile activating element (UASG)
(Bellen et al., 2004)
Size 10.908Kb
Associated alleles
Scer\UAS14x.P\T
TrlBRcRa
w+mC
y+mDint2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
capu
(Gene Disruption Project members, 2001-)
hide Alleles and Phenotypes
Causes alleles
capuEY12344
(Gene Disruption Project members, 2001-, Rosales-Nieves et al., 2006)
Lethality
References
viable
(Gene Disruption Project members, 2001-)
Sterility
References
fertile
(Gene Disruption Project members, 2001-)
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
Oocytes of wash[Δ185] capu[EY12344] transheterozygous females undergo premature cytoplasmic streaming. The normal gradient of microtubule organisation that is seen in wild-type oocytes at stage 7 is lost in the mutant oocytes. The mutant stage 7 oocytes have disruptions in the cortical actin.
(Liu et al., 2009)
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Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
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FlyView (LinkOut)
hide Data on Genetic Line
Line ID
EY12344
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
20345
y1 w67c23; P{EPgy2}capuEY12344
hide Linkouts
hide Comments
Location 2L:3884414-3884415 confirmed by FlyBase alignment of dbGSS accession CL844496 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation revised.
(FlyBase, 2005)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
P{EPgy2}capuEY12344
(FlyBase, 2005, FlyBase, 1992-)
P{EPgy2}EY12344
(FlyBase, 1992-)
Secondary FlyBase IDs
hide References ( 6 )
Research paper
Liu et al., 2009, Development 136(16): 2849--2860
Wash functions downstream of Rho and links linear and branched actin nucleation factors. [FBrf0208460]
Rosales-Nieves et al., 2006, Nature Cell Biol. 8(4): 367--376
Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire and Cappuccino. [FBrf0191267]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
FlyBase analysis
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]