A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{EPgy2}stgEY12388 Insertion

General Information
Symbol Dmel\P{EPgy2}stgEY12388 Species D. melanogaster
Name FlyBase ID FBti0040279
Feature type transposable_element_insertion_site
Description
Inserted element P{EPgy2} Expression data
Affected gene(s) stg Viability / fertility fertile, viable
Causes allele(s) stgEY12388 Stock availability 1 publicly available
LINE ID EY12388
Genomic Location
Chromosomal location 3R ( 99A5 ) Sequence location 3R:25,081,302..25,081,302 [-]
Map ( GBrowse ) detailed view FBti0126340 FBti0075531 FBti0068822 FBti0007968 FBti0069637 FBti0070349 FBti0055562 FBti0070386 FBti0055077 FBti0065938 FBti0065963 FBti0059235 FBti0113349 FBti0069386 FBti0048451 FBti0036532 FBti0011428 FBti0110478 FBti0029502 FBti0108807 FBti0005151 FBti0055519 FBti0025577 FBti0059256 FBti0068738 FBti0035955 FBti0100198 FBti0028369 FBti0110741 FBti0103819 FBti0011572 FBti0104419 FBti0105510 FBti0011569 FBti0029578 FBti0110305 FBti0013413 FBti0021488 FBti0109561 FBti0102186 FBti0040279 FBti0107369 FBti0072099 FBti0100845 FBti0109546 FBti0068474 FBti0017038 FBti0006201 FBti0017136 FBti0054465 FBti0068871 FBti0066619 FBti0045358 FBti0066480 FBti0126341_2 FBti0126341_1 FBti0033609 FBti0007937 FBti0005566 FBti0009945 FBti0052659 FBti0068722 FBti0065238
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Description
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
3R:25,081,302..25,081,302 [-]
(Gene Disruption Project members, 2001-)
Orientation
Cytological location
(computed by FlyBase)
99A5 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
99A5 (reported as inferred from sequence location)
(Gene Disruption Project members, 2001-)
Comments concerning
location
hide Sequence Data
Flanking sequence
CL844500
(Gene Disruption Project members, 2001-)
hide Inserted Element
Construct P{EPgy2}
Location-dependent
role
mobile activating element (UASG)
(Bellen et al., 2004)
Size 10.908Kb
Associated alleles
Scer\UAS14x.P\T
TrlBRcRa
w+mC
y+mDint2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
stg
(Gene Disruption Project members, 2001-)
hide Alleles and Phenotypes
Causes alleles
stgEY12388
(Gene Disruption Project members, 2001-)
Lethality
References
viable
(Gene Disruption Project members, 2001-)
Sterility
References
fertile
(Gene Disruption Project members, 2001-)
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
stg[EY12388]/+ suppresses the rough-eye phenotype and increases the number of normal photoreceptors per ommatidium in flies expressing tefu[dsRNA.Scer\UAS] under the control of Scer\GAL4[GMR.PU]. Significantly reduced severity of progressive neurodegeneration is also observed in these animals. Expression of tefu[dsRNA.Scer\UAS] under the control of Scer\GAL4[elav.PU] results in increased levels of photoreceptor cell division in third instar larval eye discs, which is suppressed by stg[EY12388]/+.
(Rimkus et al., 2008)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
EY12388
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
20349
y1 w67c23; P{EPgy2}stgEY12388
hide Linkouts
hide Comments
Location 3R:25081302-25081303 confirmed by FlyBase alignment of dbGSS accession CL844500 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation revised.
(FlyBase, 2005)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
P{EPgy2}EY12388
(FlyBase, 1992-)
P{EPgy2}stgEY12388
(FlyBase, 2005, FlyBase, 1992-)
Secondary FlyBase IDs
hide References ( 5 )
Research paper
Rimkus et al., 2008, Genes Dev. 22(9): 1205--1220
Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia. [FBrf0204663]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
FlyBase analysis
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]