Dmel\P{GAL4}repo^M1B Insertion

General Information
Symbol	Dmel\P{GAL4}repo^M1B	Species	D. melanogaster
Name		FlyBase ID	FBti0040309
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GAL4}	Expression data	GAL4 reporter/driver
Affected gene(s)	repo, Scer\GAL4	Viability / fertility
Causes allele(s)	repo^M1B, Scer\GAL4^repo-M1B	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	3R ( 90F9-90F10 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	90F9-90F10 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GAL4}
Location-dependent role	GAL4 driver/enhancer trap (FlyBase, 1992-)
Size
Associated alleles	Scer\GAL4^unspecified
Molecular map
Affected Gene(s)
Insertion may affect gene	repo (Jefferis et al., 2004, Pandey et al., 2011) Scer\GAL4 (Jefferis et al., 2004, Watts et al., 2004, Pandey et al., 2011, Kuzina et al., 2011, Ruiz et al., 2012, Miller et al., 2012, Bolkan et al., 2012)
Alleles and Phenotypes
Causes alleles	repo^M1B (Jefferis et al., 2004, Pandey et al., 2011) Scer\GAL4^repo-M1B (Jefferis et al., 2004, Watts et al., 2004, Pandey et al., 2011, Kuzina et al., 2011, Ruiz et al., 2012, Miller et al., 2012, Bolkan et al., 2012)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference A repo[M1B] heterozygous background enhances the ventral nerve cord elongation found in GlcAT-P[brv1] homozygous mutants. Correspondingly, the posterior-most peripheral nerves shorten in these mutants compared to wild-type and GlcAT-P[brv1] homozygotes. The ventral nerve cord in L2 larvae almost spans the entire length of the larva. (Pandey et al., 2011)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference adult stage CNS glial cell (Jefferis et al., 2004) glial cell \| subset (Jefferis et al., 2004) adult antennal lobe (Jefferis et al., 2004) glial cell of adult antennal lobe (Jefferis et al., 2004)
Additional Information
Statement Reference

Marker for	CNS glial cell (Jefferis et al., 2004) CNS glial cell glial cell <of> antennal lobe (Jefferis et al., 2004) glial cell <of> antennal lobe (Jefferis et al., 2004)
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	GAL4-M1B (Jefferis et al., 2004) M1B (Bolkan et al., 2012) M1B-GAL4 (Ruiz et al., 2012) MIB-Gal4 (Miller et al., 2012) P{GAL4}repo^M1B (Jefferis et al., 2004, FlyBase, 1992-) repo-GAL4 (Watts et al., 2004, Pandey et al., 2011, Bolkan et al., 2012, Kuzina et al., 2011)
Secondary FlyBase IDs

References ( 8 )
Research paper	Bolkan et al., 2012, J. Neurosci. 32(46): 16181--16192 beta-Secretase Cleavage of the Fly Amyloid Precursor Protein Is Required for Glial Survival. [FBrf0219983] Miller et al., 2012, J. Neurogenet. 26(3-4): 317--327 A mutation in Drosophila Aldolase Causes Temperature-Sensitive Paralysis, Shortened Lifespan, and Neurodegeneration. [FBrf0220234] Ruiz et al., 2012, Insect Biochem. Mol. Biol. 42(10): 776--789 Grasshopper Lazarillo, a GPI-anchored Lipocalin, increases Drosophila longevity and stress resistance, and functionally replaces its secreted homolog NLaz. [FBrf0219400] Kuzina et al., 2011, Development 138(9): 1839--1849 How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS. [FBrf0213493] Pandey et al., 2011, PLoS ONE 6(11): e28106 The Glucuronyltransferase GlcAT-P Is Required for Stretch Growth of Peripheral Nerves in Drosophila. [FBrf0216828] Jefferis et al., 2004, Development 131(1): 117--130 Developmental origin of wiring specificity in the olfactory system of Drosophila. [FBrf0167525] Watts et al., 2004, Curr. Biol. 14(8): 678--684 Glia engulf degenerating axons during developmental axon pruning. [FBrf0174493]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GAL4}repoM1B Insertion

Dmel\P{GAL4}repo^M1B Insertion