A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{EPgy2}RagCEY11726 Insertion

General Information
Symbol Dmel\P{EPgy2}RagCEY11726 Species D. melanogaster
Name FlyBase ID FBti0057958
Feature type transposable_element_insertion_site
Description
Inserted element P{EPgy2} Expression data
Affected gene(s) RagC Viability / fertility
Causes allele(s) RagCEY11726 Stock availability 1 publicly available
LINE ID EY11726
Genomic Location
Chromosomal location 2R ( 44B7 ) Sequence location 2R:4,050,912..4,050,912 [+]
Map ( GBrowse ) detailed view FBti0125031_2 FBti0125031_1 FBti0108198 FBti0111605 FBti0106904 FBti0029699 FBti0077947 FBti0021334 FBti0044645 FBti0047716 FBti0047571 FBti0067447 FBti0053213 FBti0024524 FBti0057958 FBti0126694 FBti0047333 FBti0066695 FBti0006573 FBti0125032 FBti0125033_1 FBti0125033_2 FBti0043038 FBti0041358 FBti0076003
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Description
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
2R:4,050,912..4,050,912 [+]
(Gene Disruption Project members, 2001-)
Orientation
Cytological location
(computed by FlyBase)
44B7 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
44B9 (reported as inferred from sequence location)
(Gene Disruption Project members, 2001-)
Comments concerning
location
hide Sequence Data
Flanking sequence
CW848180
(Gene Disruption Project members, 2001-)
hide Inserted Element
Construct P{EPgy2}
Location-dependent
role
mobile activating element (UASG)
(Bellen et al., 2004)
Size 10.908Kb
Associated alleles
Scer\UAS14x.P\T
TrlBRcRa
w+mC
y+mDint2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
RagC
(Gene Disruption Project members, 2001-, Kim et al., 2008)
hide Alleles and Phenotypes
Causes alleles
RagCEY11726
(Gene Disruption Project members, 2001-, Kim et al., 2008)
Lethality
References
lethal | third instar larval stage
(Kim et al., 2008)
Sterility
References
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
Under normal fed conditions, RagC[EY11726] clones in the larval fat body show in a potent decrease in cell size compared with neighbouring control cells. Under starvation conditions, RagC[EY11726] clones in the larval fat body have no effect on cell size compared to controls.
(Kim et al., 2008)
The increase in cell area relative to control cells that is seen in cells in the fat body that are expressing Rheb[EP50.084-loxP] is enhanced if the animals are also homozygous for RagC[EY11726].
(Kim et al., 2008)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
EY11726
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
21364
y1 w67c23; P{EPgy2}RagCEY11726/CyO
hide Linkouts
hide Comments
Location 2R:3675220-3675221 confirmed by FlyBase alignment of dbGSS accession CW848180 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation confirmed.
(FlyBase, 2005)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
P{EPgy2}CG8707EY11726
(FlyBase, 2005, FlyBase, 1992-)
P{EPgy2}EY11726
(FlyBase, 1992-)
P{EPgy2}RagCEY11726
 
PEPgy2EY11726
(Kim et al., 2008)
Secondary FlyBase IDs
hide References ( 5 )
Research paper
Kim et al., 2008, Nat. Cell Biol. 10(8): 935--945
Regulation of TORC1 by Rag GTPases in nutrient response. [FBrf0206857]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
FlyBase analysis
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]