Dmel\P{EPgy2}mip40^EY16520 Insertion

General Information
Symbol	Dmel\P{EPgy2}mip40^EY16520	Species	D. melanogaster
Name		FlyBase ID	FBti0070904
Feature type	transposable_element_insertion_site
Description
Inserted element	P{EPgy2}	Expression data
Affected gene(s)	mip40	Viability / fertility
Causes allele(s)	mip40^EY16520	Stock availability	1 publicly available
LINE ID	EY16520
Genomic Location
Chromosomal location	2R ( 56C8 )	Sequence location	2R:15,179,429..15,179,429
Map ( GBrowse )
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
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Detailed Mapping Data
Chromosome (arm)
Sequence Location	2R:15,179,429..15,179,429 (Gene Disruption Project members, 2001-)
Orientation
Cytological location (computed by FlyBase)	56C8 ( inferred by FlyBase from sequence location )
Cytological location (reported)	56C8 (reported as inferred from sequence location) (Gene Disruption Project members, 2001-)
Comments concerning location
Sequence Data
Flanking sequence	CW627924 (Gene Disruption Project members, 2001-)
Inserted Element
Construct	P{EPgy2}
Location-dependent role	mobile activating element (UASG) (Bellen et al., 2004)
Size	10.908Kb
Associated alleles	Scer\UAS^14x.P\T TrlBR^cRa w^+mC y^+mDint2
Molecular map
Affected Gene(s)
Insertion may affect gene	mip40 (Gene Disruption Project members, 2001-, Beall et al., 2007)
Alleles and Phenotypes
Causes alleles	mip40^EY16520 (Gene Disruption Project members, 2001-, Beall et al., 2007)

Lethality References viable (Beall et al., 2007)
Sterility References female sterile \| recessive (Beall et al., 2007) male sterile \| recessive (Beall et al., 2007)
Phenotype Manifest In
	testis (Beall et al., 2007)
Detailed Description
Statement Reference Most homozygous females are completely sterile, while a few give rise to one or two larvae after 7 days of egg laying. Many nuclei within homozygous stage 10 egg chambers have a normal BrdU incorporation pattern (in four foci). However, within the same mutant egg chamber at this stage there are also nuclei that have BrdU incorporation spread throughout the entire nucleus. Homozygous males are sterile. The mutant testes completely lack mature sperm and development appears to be arrested at the primary spermatocyte stage, prior to the G2-M transition. (Beall et al., 2007)
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID	EY16520 (Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	21217 y¹ w^67c23; P{EPgy2}mip40^EY16520/CyO
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{EPgy2}EY16520 (FlyBase, 1992-) P{EPgy2}mip40^EY16520 (FlyBase, 1992-)
Secondary FlyBase IDs

References ( 4 )
Research paper	Beall et al., 2007, Genes Dev. 21(8): 904--919 Discovery of tMAC: a Drosophila testis-specific meiotic arrest complex paralogous to Myb-Muv B. [FBrf0200827] Bellen et al., 2004, Genetics 167(2): 761--781 The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177]

Dmel\P{EPgy2}mip40EY16520 Insertion

Dmel\P{EPgy2}mip40^EY16520 Insertion