A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\Mi{ET1}wryMB00103 Insertion

General Information
Symbol Dmel\Mi{ET1}wryMB00103 Species D. melanogaster
Name FlyBase ID FBti0076194
Feature type transposable_element_insertion_site
Description
Inserted element Mi{ET1} Expression data
Affected gene(s) wry Viability / fertility fertile, viable
Causes allele(s) wryMB00103 Stock availability 1 publicly available
LINE ID MB00103
Genomic Location
Chromosomal location 2L ( 22B4 ) Sequence location 2L:1,853,062..1,853,062 [-]
Map ( GBrowse ) detailed view FBti0049090 FBti0132593 FBti0076194 FBti0075271
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Description
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This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
2L:1,853,062..1,853,062 [-]
(Bellen, 2006.8.3)
Orientation
Cytological location
(computed by FlyBase)
22B4 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
22B4 (reported as inferred from sequence location)
(Bellen, 2006.8.3)
Comments concerning
location
hide Sequence Data
Flanking sequence
DX977968
(Bellen, 2006.8.3)
hide Inserted Element
Construct Mi{ET1}
Location-dependent
role
GAL4 driver/enhancer trap
(Metaxakis et al., 2005)
Size 7.5, 7.5Kb
Associated alleles
Avic\GFPE.3xP3
Scer\GAL4ET1
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
wry
(Bellen, 2006.8.3)
hide Alleles and Phenotypes
Causes alleles
wryMB00103
(Bellen, 2006.8.3)
Lethality
References
viable
(Bellen, 2006.8.3)
Sterility
References
fertile
(Bellen, 2006.8.3)
hide Phenotype Manifest In
adult heart
(Kim et al., 2010)
hide Detailed Description
Statement
Reference
wry[MB00103] flies display abnormal cardiac function. Animals show dilated cardiomyopathy, defined as enlarged end-diastolic and end-systolic dimensions, and impaired fractional shortening.
(Kim et al., 2010)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
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FlyView (LinkOut)
hide Data on Genetic Line
Line ID
MB00103
(Bellen, 2006.8.3)
Origin as a multiple insertion line
N
(Bellen, 2006.8.3)
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
22697
y1 w67c23; Mi{ET1}wryMB00103
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hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
Mi{ET1}CG31665MB00103
(Bellen, 2006.8.3)
Mi{ET1}wryMB00103
 
Secondary FlyBase IDs
hide References ( 5 )
Research paper
Kim et al., 2010, Circulation Res. 106(7): 1233--1243
Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand. [FBrf0210603]
Metaxakis et al., 2005, Genetics 171(2): 571--581
Minos as a genetic and genomic tool in Drosophila melanogaster. [FBrf0190750]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Personal communication to FlyBase
Bellen, 2006.8.3, MBBatch686.xml
MBBatch686.xml [FBrf0191806]
FlyBase analysis
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]