Dmel\P{GawB}VGlut^OK371 Insertion

General Information
Symbol	Dmel\P{GawB}VGlut^OK371	Species	D. melanogaster
Name		FlyBase ID	FBti0076967
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4, VGlut	Viability / fertility	viable
Causes allele(s)	Scer\GAL4^VGlut-OK371, VGlut^OK371	Stock availability	1 publicly available
LINE ID
Genomic Location
Chromosomal location	2L ( 22E1 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	22E1 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Venkiteswaran and Hasan, 2009, Mahr and Aberle, 2006, Meyer and Aberle, 2006, Beuchle et al., 2007, Grosjean et al., 2008, Cheng et al., 2011, Diegelmann et al., 2008, Abou Tayoun et al., 2011, Jepson et al., 2012, Keegan et al., 2011, Shao et al., 2011, Keller et al., 2011, Pulver et al., 2009, Baek and Mann, 2009, Koch et al., 2008, Gao et al., 2008, Johnson et al., 2009, Gao et al., 2008, Kolodziejczyk et al., 2008, Nässel et al., 2008, Boerner and Duch, 2010, Melicharek et al., 2010, Nedelsky et al., 2010, de Haro et al., 2010, Yu et al., 2010, Nicolaï et al., 2010, Cognigni et al., 2011, Slawson et al., 2011, Lanson et al., 2011, Hornstein et al., 2009, Li et al., 2010, Jepson et al., 2011, Beck et al., 2012, Majumdar et al., 2012, Jochum et al., 2012, Jansen et al., 2009, Lloyd et al., 2012, Panz et al., 2012, Xia et al., 2012, Lotti et al., 2012, Li et al., 2010, Dickman et al., 2012) VGlut (Mahr and Aberle, 2006, Baek and Mann, 2009)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^VGlut-OK371 (Venkiteswaran and Hasan, 2009, Mahr and Aberle, 2006, Meyer and Aberle, 2006, Beuchle et al., 2007, Grosjean et al., 2008, Cheng et al., 2011, Diegelmann et al., 2008, Abou Tayoun et al., 2011, Jepson et al., 2012, Keegan et al., 2011, Shao et al., 2011, Keller et al., 2011, Pulver et al., 2009, Baek and Mann, 2009, Koch et al., 2008, Gao et al., 2008, Johnson et al., 2009, Gao et al., 2008, Kolodziejczyk et al., 2008, Nässel et al., 2008, Boerner and Duch, 2010, Melicharek et al., 2010, Nedelsky et al., 2010, de Haro et al., 2010, Yu et al., 2010, Nicolaï et al., 2010, Cognigni et al., 2011, Slawson et al., 2011, Lanson et al., 2011, Hornstein et al., 2009, Li et al., 2010, Jepson et al., 2011, Beck et al., 2012, Majumdar et al., 2012, Jochum et al., 2012, Jansen et al., 2009, Lloyd et al., 2012, Panz et al., 2012, Xia et al., 2012, Lotti et al., 2012, Li et al., 2010, Dickman et al., 2012) VGlut^OK371 (Baek and Mann, 2009)

Lethality References viable (Mahr and Aberle, 2006)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference larval stage embryonic/larval protocerebrum \| restricted (Nässel et al., 2008) mushroom body beta-lobe \| surrounding (Nässel et al., 2008) ventral nerve cord (Nässel et al., 2008) third instar larval stage glutamatergic neuron (de Haro et al., 2010) adult stage glutamatergic neuron (Kolodziejczyk et al., 2008) medulla layer M6 \| restricted (Gao et al., 2008)
Additional Information
Statement Reference Expression of Scer\GAL4[VGlut-OK371], which reflects expression of VGlut, within the protocerebrum, is seen within a dorso-laterally located group of cells, and where it colocalizes with sNPF protein. Expression of Scer\GAL4[VGlut-OK371] in the nerve cord is extensive. (Nässel et al., 2008)

Marker for	glutamatergic neuron (Kolodziejczyk et al., 2008)
Reflects expression of
Reporter construct used in assay	Mmus\Cd8a^{Scer\UAS.T:Avic\GFP} (Nässel et al., 2008, Kolodziejczyk et al., 2008, de Haro et al., 2010) n-syb^{Scer\UAS.T:Avic\GFP-EGFP} (Kolodziejczyk et al., 2008)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	26160 w¹¹¹⁸; P{GawB}VGlut^OK371
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	Glutamatergic GAL4 (Venkiteswaran and Hasan, 2009) OK371 (Venkiteswaran and Hasan, 2009, Yu et al., 2010, Keegan et al., 2011, Majumdar et al., 2012) Ok371 (Jepson et al., 2011) OK371-Gal4 (Mahr and Aberle, 2006, Cheng et al., 2011, Panz et al., 2012, Meyer and Aberle, 2006, Beuchle et al., 2007, Diegelmann et al., 2008, Baek and Mann, 2009, Koch et al., 2008, Gao et al., 2008, Kolodziejczyk et al., 2008, Nässel et al., 2008, Melicharek et al., 2010, Cognigni et al., 2011, Slawson et al., 2011, Abou Tayoun et al., 2011, Li et al., 2010, Jepson et al., 2012, Beck et al., 2012, Xia et al., 2012, Lotti et al., 2012) OK371-GAL4 (Nicolaï et al., 2010, Pulver et al., 2009, Johnson et al., 2009, Boerner and Duch, 2010, Nedelsky et al., 2010, de Haro et al., 2010, Lanson et al., 2011, Hornstein et al., 2009, Dickman et al., 2012, Keller et al., 2011, Jochum et al., 2012, Jansen et al., 2009, Lloyd et al., 2012) OK371Gal4 (Grosjean et al., 2008) ok371-GAL4 (Li et al., 2010) P{GawB}OK371 (Johnson et al., 2009, FlyBase, 1992-) P{GawB}VGlut^OK371 vesciular glutamate transporter-galactosidase-4 (Baek and Mann, 2009) vesicular glutamate transporter Gal4 (Shao et al., 2011) vGlut^OK371-Gal4 (Gao et al., 2008) Vglut-Gal4 (Baek and Mann, 2009) vGlut-Gal4 (Gao et al., 2008) vGluT-Gal4 (Kolodziejczyk et al., 2008) VGlut-GAL4 (de Haro et al., 2010) VGlut-Gal4 (Shao et al., 2011)
Secondary FlyBase IDs

References ( 44 )

Generate a list of	All references relating to this insertion ( 44 )

List References by type	Research paper ( 42 ) Supplementary material ( 1 ) FlyBase analysis ( 1 )
Recent research papers ( 18 )
	Beck et al., 2012, J. Neurosci. 32(20): 7058--7073 Regulation of Fasciclin II and Synaptic Terminal Development by the Splicing Factor Beag. [FBrf0218385] Dickman et al., 2012, J. Neurosci. 32(25): 8716--8724 Snapin is Critical for Presynaptic Homeostatic Plasticity. [FBrf0218676] Jepson et al., 2012, PLoS Genet. 8(4): e1002671 dyschronic, a Drosophila Homolog of a Deaf-Blindness Gene, Regulates Circadian Output and Slowpoke Channels. [FBrf0218124] Jochum et al., 2012, Biochim. Biophys. Acta 1822(6): 1070--1078 Toxic and non-toxic aggregates from the SBMA and normal forms of androgen receptor have distinct oligomeric structures. [FBrf0218222] Lloyd et al., 2012, Neuron 74(2): 344--360 The p150(Glued) CAP-Gly Domain Regulates Initiation of Retrograde Transport at Synaptic Termini. [FBrf0218160] Lotti et al., 2012, Cell 151(2): 440--454 An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function. [FBrf0219670] Majumdar et al., 2012, Cell 148(3): 515--529 Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory. [FBrf0217407] Panz et al., 2012, Biol. Cell 104(9): 553--568 A novel role for the non-catalytic intracellular domain of Neprilysins in muscle physiology. [FBrf0219388] Xia et al., 2012, Mol. Neurodegener. 7: 10 Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS. [FBrf0218020] Abou Tayoun et al., 2011, J. Neurosci. 31(39): 13897--13910 The Drosophila SK Channel (dSK) Contributes to Photoreceptor Performance by Mediating Sensitivity Control at the First Visual Network. [FBrf0216279] Cheng et al., 2011, J. Cell Biol. 194(6): 921--935 S6 kinase localizes to the presynaptic active zone and functions with PDK1 to control synapse development. [FBrf0216911] Cognigni et al., 2011, Cell Metab. 13(1): 92--104 Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis. [FBrf0212594] Jepson et al., 2011, J. Biol. Chem. 286(10): 8325--8337 Engineered Alterations in RNA Editing Modulate Complex Behavior in Drosophila: REGULATORY DIVERSITY OF ADENOSINE DEAMINASE ACTING ON RNA (ADAR) TARGETS. [FBrf0213236] Keegan et al., 2011, Nucleic Acids Res. 39(16): 7249--7262 Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects. [FBrf0215032] Keller et al., 2011, Neuron 72(5): 760--775 Glial-derived prodegenerative signaling in the Drosophila neuromuscular system. [FBrf0216904] Lanson et al., 2011, Hum. Mol. Genet. 20(13): 2510--2523 A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43. [FBrf0213887] Shao et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(46): 18831--18836 Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila. [FBrf0216775] Slawson et al., 2011, Genetics 187(1): 171--184 Central Regulation of Locomotor Behavior of Drosophila melanogaster Depends on a CASK Isoform Containing CaMK-Like and L27 Domains. [FBrf0212754] Show all research papers ...

Dmel\P{GawB}VGlutOK371 Insertion

Dmel\P{GawB}VGlut^OK371 Insertion