Dmel\P{GT1}neur^BG02391 Insertion

General Information
Symbol	Dmel\P{GT1}neur^BG02391	Species	D. melanogaster
Name		FlyBase ID	FBti0077215
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GT1}	Expression data
Affected gene(s)	neur	Viability / fertility
Causes allele(s)	neur^BG02391	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	3R ( 85C2-85C3 )	Sequence location
Member of Large Scale Dataset(s)
Dataset	TI_set_P{GT1}.BG A set of transgenic insertion stocks derived by TE mobilization using the P-element construct P{GT1}; created and vetted by the Gene Disruption Project (GDP). The P{GT1} construct is described as a dual-tagged gene trap (FBrf0132344):it carries (1) w[+mGT1] mini-white marker, designed to confer a pigmented eye phenotype only if the construct is inserted within a host gene, and (2) a promoter-less Ser\GAL4 gene which is expressed if it is produced as a fusion with the mRNA produced by the host gene. The construct also carries a Tn\neoR selectable marker (FBrf0132344). (Bellen et al., 2004)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	References Bellen et al., 2004, Genetics 167(2): 761--781
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	85C2-85C3 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GT1}
Location-dependent role	GAL4 gene trap (Lukacsovich and Asztalos, 1999.7.15)
Size	8.447, 8.447Kb
Associated alleles	Scer\GAL4^GT1 Tn\neoR^Hsp70Bb.PS w^+mGT
Molecular map
Affected Gene(s)
Insertion may affect gene	neur (Sambandan et al., 2006, Rollmann et al., 2008)
Alleles and Phenotypes
Causes alleles	neur^BG02391 (Sambandan et al., 2006, Rollmann et al., 2008)

Lethality References viable (Sambandan et al., 2006)
Sterility References
Phenotype Manifest In
	ellipsoid body (Rollmann et al., 2008) microchaeta & sternite \| male (Rollmann et al., 2008) mushroom body alpha-lobe (Rollmann et al., 2008) sternopleural bristle \| female (Rollmann et al., 2008) sternopleural bristle \| male (Rollmann et al., 2008)
Detailed Description
Statement Reference Homozygous males and females show a significant reduction in the number of sternopleural bristles compared to controls. Homozygous males show a significant reduction in the number of abdominal bristles compared to controls. Mutant flies show reduced behavioural avoidance responses to benzaldehyde compared to controls. Mutants show normal locomotor activity. The average number of aggressive encounters by males competing for a limited food supply after a period of food deprivation is approximately 1.8 fold greater in neur[BG02391] males than in controls. Gross morphological defects are not seen in the α-lobes of the mushroom body or in the ellipsoid body of neur[BG02587] adults. However, detailed morphometric analysis reveals that the width of the α- and β-lobes is significantly increased in neur[BG02391] adults compared to controls and that the neur[BG02391] animals show a reduction in ellipsoid body surface. (Rollmann et al., 2008) Mutants show a reduced olfactory avoidance response to 0.03, 0.10 or 0.30% benzaldehyde compared to control flies, while the avoidance response is not significantly from that of control flies at benzaldehyde concentrations of 1.0 or 3.0%. (Sambandan et al., 2006)
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{GT1}neur^BG02391 (FlyBase, 1992-, )
Secondary FlyBase IDs

References ( 6 )
Research paper	Rollmann et al., 2008, Genetics 179(3): 1327--1336 Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. [FBrf0207167] Sambandan et al., 2006, Genetics 174(3): 1349--1363 Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. [FBrf0192106] Bellen et al., 2004, Genetics 167(2): 761--781 The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Personal communication to FlyBase	Lukacsovich and Asztalos, 1999.7.15, Dual tagging gene-trap of novel genes in Drosophila melanogaster. Dual tagging gene-trap of novel genes in Drosophila melanogaster. [FBrf0108534]
FlyBase analysis	FlyBase Curators, 2013, Members of GDP insertion collections: P{GT1}, P{SUPor-P}, P{EPgy2}, Mi{ET1}, Mi{MIC}. Members of GDP insertion collections: P{GT1}, P{SUPor-P}, P{EPgy2}, Mi{ET1}, Mi{MIC}. [FBrf0220667] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GT1}neurBG02391 Insertion

Dmel\P{GT1}neur^BG02391 Insertion