A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Dmel\P{GT1}neurBG02587 Insertion

General Information
Symbol Dmel\P{GT1}neurBG02587 Species D. melanogaster
Name FlyBase ID FBti0115114
Feature type transposable_element_insertion_site
Description
Inserted element P{GT1} Expression data
Affected gene(s) neur Viability / fertility
Causes allele(s) neurBG02587 Stock availability none publicly available
LINE ID BG02587
Genomic Location
Chromosomal location 3R ( 85C3 ) Sequence location 3R:4,859,506..4,859,506 [-]
Map ( GBrowse ) GBrowse View Help detailed view FBti0049421 FBti0143007 FBti0009075 FBti0125983 FBti0044526 FBti0007960 FBti0013419 FBti0104479 FBti0111291 FBti0115114 FBti0146124 FBti0034410 FBti0005628 FBti0016492 FBti0033467 FBti0023530 FBti0111756 FBti0112353 FBti0110408 FBti0102545 FBti0029096 FBti0028795 FBti0106306 FBti0059198 FBti0035302 FBti0106449 FBti0035301 FBti0034102 FBti0112073 FBti0104609 FBti0105318 FBti0047114 FBti0066118 FBti0143257 FBti0043373 FBti0066410 FBti0068188 FBti0033478 FBti0016448 FBti0113211 FBti0039383
Member of Large Scale Dataset(s)
Dataset

A set of transgenic insertion stocks derived by TE mobilization using the P-element construct P{GT1}; created and vetted by the Gene Disruption Project (GDP). The P{GT1} construct is described as a dual-tagged gene trap (FBrf0132344):it carries (1) w[+mGT1] mini-white marker, designed to confer a pigmented eye phenotype only if the construct is inserted within a host gene, and (2) a promoter-less Ser\GAL4 gene which is expressed if it is produced as a fusion with the mRNA produced by the host gene. The construct also carries a Tn\neoR selectable marker (FBrf0132344).
(Bellen et al., 2004)
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Description
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FB2013_03
References
Bellen et al., 2004, Genetics 167(2): 761--781
FB2013_02
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
3R:4,859,506..4,859,506 [-]
(Levis et al., 2011.12.16)
Orientation
-
(Levis et al., 2011.12.16)
Cytological location
(computed by FlyBase)
85C3 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
85C3_r5 (reported as inferred from sequence location)
(Levis et al., 2011.12.16)
Comments concerning
location
hide Sequence Data
Flanking sequence
hide Inserted Element
Construct P{GT1}
Location-dependent
role
GAL4 gene trap
(Lukacsovich and Asztalos, 1999.7.15)
Size 8.447, 8.447Kb
Associated alleles
Scer\GAL4GT1
Tn\neoRHsp70Bb.PS
w+mGT
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
neur
(Levis et al., 2011.12.16, Rollmann et al., 2008)
hide Alleles and Phenotypes
Causes alleles
neurBG02587
(Levis et al., 2011.12.16, Rollmann et al., 2008)
Lethality
References
Sterility
References
hide Phenotype Manifest In
microchaeta & sternite | female
(Rollmann et al., 2008)
hide Detailed Description
Statement
Reference
Homozygous flies show no significant change in the number of sternopleural bristles compared to controls. Homozygous females show a significant reduction in the number of abdominal bristles compared to controls. Mutant flies show a normal behavioural avoidance response to benzaldehyde in an olfactory assay. Mutant males and females show a significant reduction in locomotor activity compared to controls. The average number of aggressive encounters by males competing for a limited food supply after a period of food deprivation is approximately 1.8 fold greater in neur[BG02587] males than in controls. Gross morphological defects are not seen in the α-lobes of the mushroom body or in the ellipsoid body of neur[BG02587] adults.
(Rollmann et al., 2008)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
Reporter construct
used in assay
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
BG02587
(Levis et al., 2011.12.16)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 0 )
hide Linkouts
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
BG02587
(Levis et al., 2011.12.16)
P{GT1}neurBG02587
(FlyBase, 1992-)
Secondary FlyBase IDs
hide References ( 6 )
Research paper
Rollmann et al., 2008, Genetics 179(3): 1327--1336
Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. [FBrf0207167]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Personal communication to FlyBase
Levis et al., 2011.12.16, Insertion site data for additional GT1 (BG) lines.
Insertion site data for additional GT1 (BG) lines. [FBrf0217018]
Lukacsovich and Asztalos, 1999.7.15, Dual tagging gene-trap of novel genes in Drosophila melanogaster.
Dual tagging gene-trap of novel genes in Drosophila melanogaster. [FBrf0108534]
FlyBase analysis
FlyBase Curators, 2013, Members of GDP insertion collections: P{GT1}, P{SUPor-P}, P{EPgy2}, Mi{ET1}, Mi{MIC}.
Members of GDP insertion collections: P{GT1}, P{SUPor-P}, P{EPgy2}, Mi{ET1}, Mi{MIC}. [FBrf0220667]
FlyBase, 1992-, FlyBase curation.
FlyBase curation. [FBrf0105495]