Dmel\P{GawB}C5^C5 Insertion

General Information
Symbol	Dmel\P{GawB}C5^C5	Species	D. melanogaster
Name		FlyBase ID	FBti0129919
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	C5, Scer\GAL4	Viability / fertility
Causes allele(s)	C5^C5, Scer\GAL4^C5	Stock availability	1 publicly available
LINE ID
Genomic Location
Chromosomal location	3	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
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FB2013_03
FB2013_02
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Detailed Mapping Data
Chromosome (arm)	3 (Young and Armstrong, 2010, Cook, 2010.7.28)
Sequence Location
Orientation
Cytological location (computed by FlyBase)
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	C5 (Martin et al., 1999) Scer\GAL4 (Xiong et al., 2010, Angus et al., 2012, Troost et al., 2012, Liu et al., 2006, Yeh et al., 1995, Tsuda et al., 2005, True et al., 1999, Jafar-Nejad et al., 2003, Udan et al., 2003, Quan et al., 2004, Martin et al., 1999, Fernandez-Funez et al., 1998, Rodriguez-Esteban et al., 1998, Cohen et al., 1997, Rives et al., 2006, Lam et al., 2006, Childress et al., 2006, Seto and Bellen, 2006, Childress et al., 2006, Hayward et al., 2005, Wang et al., 2008, Young and Armstrong, 2010, Kahsai et al., 2010, Young and Armstrong, 2010, Ajuria et al., 2011, Zhao et al., 2009, Tsuda et al., 2008)
Alleles and Phenotypes
Causes alleles	C5^C5 (Martin et al., 1999) Scer\GAL4^C5 (Xiong et al., 2010, Angus et al., 2012, Troost et al., 2012, Yeh et al., 1995, Tsuda et al., 2005, True et al., 1999, Jafar-Nejad et al., 2003, Udan et al., 2003, Quan et al., 2004, Martin et al., 1999, Fernandez-Funez et al., 1998, Rodriguez-Esteban et al., 1998, Cohen et al., 1997, Rives et al., 2006, Lam et al., 2006, Childress et al., 2006, Seto and Bellen, 2006, Childress et al., 2006, Hayward et al., 2005, Liu et al., 2006, Wang et al., 2008, Young and Armstrong, 2010, Kahsai et al., 2010, Young and Armstrong, 2010, Ajuria et al., 2011, Zhao et al., 2009, Tsuda et al., 2008)

Lethality References viable (Martin et al., 1999)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference Heterozygous adults show a substantial increase in locomotor activity compared to wild type. (Martin et al., 1999)
Expression Data
Reporter Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference third instar larval stage wing disc \| restricted (Yeh et al., 1995) distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference adult stage large field neuron \| vicinity of (Martin et al., 1999) Comment:expression is tangential to large field fan-shaped body \| dorsal & ventral (Young and Armstrong, 2010) lateral fan-shaped neuron ExFl1 (Young and Armstrong, 2010) lateral fan-shaped neuron ExFl2 (Young and Armstrong, 2010)
Additional Information
Statement Reference Adult expression is observed in a cluster of five or six tangential large field neurons with cell bodies located in the dorso-caudal cellular cortex lateral to the calyx of the mushroom body. The axons of these neurons arborize in the rostro-dorsal protocerebrum, near the tip of the α'-lobe of the mushroom body, and dorsally in the fan-shaped body. Additional faint expression is observed in the mushroom bodies. (Martin et al., 1999)

Marker for	large field neuron \| tangential (Martin et al., 1999)
Reflects expression of
Reporter construct used in assay	Mmus\Cd8a^{Scer\UAS.T:Avic\GFP} (Young and Armstrong, 2010, Young and Armstrong, 2010)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	30839 w^*; P{GawB}C5^C5
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	c5 (Liu et al., 2006, Wang et al., 2008, Young and Armstrong, 2010, Kahsai et al., 2010, Young and Armstrong, 2010) C5 (Angus et al., 2012) C5-GAL4 (Xiong et al., 2010, Tsuda et al., 2005, Jafar-Nejad et al., 2003, Fernandez-Funez et al., 1998, Lam et al., 2006, Ajuria et al., 2011, Tsuda et al., 2008) C5-Gal4 (Troost et al., 2012, Zhao et al., 2009, Childress et al., 2006, Udan et al., 2003, Rives et al., 2006, Seto and Bellen, 2006, Childress et al., 2006) C5Gal4 (Quan et al., 2004, Hayward et al., 2005) P[GAL4]C5 (Martin et al., 1999) P{GAL4}c5 P{GawB}C5 (FlyBase, 1992-) P{GawB}C5^C5 (Cook, 2010.7.28, FlyBase, 1992-) P^GAL4 C5 (Martin et al., 1999)
Secondary FlyBase IDs
	FBti0002758 FBti0074328
References ( 30 )

Generate a list of	All references relating to this insertion ( 30 )

List References by type	Research paper ( 27 ) Supplementary material ( 1 ) Personal communication to FlyBase ( 1 ) FlyBase analysis ( 1 )
Recent research papers ( 3 )
	Angus et al., 2012, Oncogene 31(2): 238--250 Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP. [FBrf0217212] Troost et al., 2012, J. Cell Sci. 125(3): 763--776 The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4. [FBrf0217584] Ajuria et al., 2011, Development 138(5): 915--924 Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila. [FBrf0212975] Show all research papers ...

Dmel\P{GawB}C5C5 Insertion

Dmel\P{GawB}C5^C5 Insertion