FB2025_04 , released October 2, 2025
Experimental tool: BoNT-C-LC
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General Information
Symbol
BoNT-C-LC
FlyBase ID
FBto0000742
Name
botulinum neurotoxin type C light chain
Description
Description

BoNT-C-LC corresponds to the light chain of Clostridium botulinum neurotoxin type C. BoNT-C-LC can be used as a tool to inhibit neuron activity; it is an endopeptidase that selectively cleaves both syntaxin and SNAP-25, resulting in synaptic vesicles that cannot undergo the normal cycle of exocytosis and endocytosis and preventing neurotransmitter release (reviewed in PMID:15979165).

External Crossreferences and Linkouts
Related experimental tools
Transgenic Constructs
Encodes tool (3)
Insertions ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
BoNT-C-LC
BoNT/C-LC
Name Synonyms
botulinum neurotoxin type C light chain
Secondary FlyBase IDs
    References (4)