FB2025_01 , released February 20, 2025
Recombinant Construct: P{UAS-Delta::N.ΔECN}
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General Information
Symbol
P{UAS-Delta::N.ΔECN}
FlyBase ID
FBtp0001306
Feature type
transgenic_transposable_element
Component Allele(s)
Also Known As
UAS-ΔN34a, UAS-NotchACT, UAS-NACT, UAS-Nintra, UAS-NΔE, UAS-NΔB2a2, UAS-NΔecd, UAS-actN, UAS-NCA, UAS-NICD
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
Component allele Delta::NΔECN.UAS
Transgenic product class
Component
Use(s)
Encoded product / tool
Description

UASt regulatory sequences drive expression of a constitutively activated, ligand-independent form of N. The signal sequence and signal cleavage site of Dl (amino acid residues 1-27) are fused to N sequence from amino acid 1742 to the end of the coding sequence. A frameshift mutation in the N coding sequence causes premature termination after amino acid residue 2235 with 4 residues (RPPT) appended to the C terminus.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments

construct_comment: Obtained from E. Giniger.

report comment: Notch protein produced is constitutively active.

Stocks (3)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (39)
Reported As
Symbol Synonym
P(UAS-Dl::N.ΔECN)
P{UAS-Delta::N.ΔECN}
P{UAS-Dl::N.DeltaECN}
P{UAS-Dl::N.act}
P{w+mC = UAS-Dl::N.ΔECN}
UAS-N-DeltaEN
UAS-NΔ34a
UAS-NΔECN
UAS-Notch+Delta
UAS-Notch-intra
Secondary FlyBase IDs
  • FBtp0001310
References (67)