Recombinant construct P{UAS-dap.L}

General Information
Symbol	P{UAS-dap.L}	FlyBase ID	FBtp0001369
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	0 available
Molecular map
Recent Updates
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Lane et al., 1996)
Uses	CV term Qualifiers & info Reference binary system (targeted) dap (Lane et al., 1996) characterization dap (Lane et al., 1996)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Lane et al., 1996) chimeric gene (Lane et al., 1996) selectable marker (Lane et al., 1996)
Component Alleles
Allele	dap^Scer\UAS.cLa
Reference(s)	(Lane et al., 1996, Han and Bodmer, 2003, Weiss et al., 1998, Calvi et al., 1998, Audibert et al., 2005, Szuplewski et al., 2003, Delanoue et al., 2002, Remaud et al., 2008, Duman-Scheel et al., 2004, Duman-Scheel et al., 2002, Wang et al., 2006, Berger et al., 2005, Legent et al., 2006, Shibutani et al., 2007, Ninov et al., 2007, Brun et al., 2006, van de Bor et al., 1999, Zielke et al., 2006, Delanoue et al., 2004, Gupta et al., 2008)
Molecular data	Construct: Scer\GAL4 Scer\UAS binding sites are fused upstream of dap cDNA sequences. (Lane et al., 1996)
Phenotypic class	female sterile, with Scer\GAL4^c323 (Calvi et al., 1998) mitotic cell cycle defective, with Scer\GAL4^neur-P72 (Audibert et al., 2005) neuroanatomy defective, with Scer\GAL4^sca-537.4 (Berger et al., 2005) size defective, with Scer\GAL4^ey.PH (Gupta et al., 2008) visible, with Scer\GAL4^GMR.PF (Gupta et al., 2008) visible, with Scer\GAL4^ptc-559.1 (Legent et al., 2006) visible, with Scer\GAL4^vg.int2.1 (Legent et al., 2006)
Phenotype manifest in	adult abdomen \| somatic clone, with Scer\GAL4^Act5C.PI (Ninov et al., 2007) cardioblast, with Scer\GAL4^twi.PG (Han and Bodmer, 2003) chorion, with Scer\GAL4^c323 (Calvi et al., 1998) dorsal appendage, with Scer\GAL4^c323 (Calvi et al., 1998) egg, with Scer\GAL4^c323 (Calvi et al., 1998) embryonic/larval epidermis \| somatic clone, with Scer\GAL4^Act5C.PI (Ninov et al., 2007) embryonic pericardial cell, with Scer\GAL4^eve.eme (Han and Bodmer, 2003) embryonic pericardial cell, with Scer\GAL4^twi.PG (Han and Bodmer, 2003) eye, with Scer\GAL4^GMR.PF (Gupta et al., 2008) eye disc posterior to the morphogenetic furrow \| somatic clone, with Scer\GAL4^GMR.PU (Zielke et al., 2006) G1 phase & external sensory organ precursor cell IIa, with Scer\GAL4^neur-P72 (Audibert et al., 2005) G1 phase & external sensory organ precursor cell IIb, with Scer\GAL4^neur-P72 (Audibert et al., 2005) histoblast \| somatic clone, with Scer\GAL4^Act5C.PI (Ninov et al., 2007) neuroblast NB6-4 of thorax, with Scer\GAL4^sca-537.4 (Berger et al., 2005) neuron & embryonic thorax, with Scer\GAL4^sca-537.4 (Berger et al., 2005) wing, with Scer\GAL4^vg.int2.1 (Legent et al., 2006) wing disc, with Scer\GAL4^ptc-559.1 (Legent et al., 2006) wing margin, with Scer\GAL4^ptc-559.1 (Legent et al., 2006)
Other information

Allele	w^+mC
Reference(s)	(Lane et al., 1996)
Molecular data	Minigene of the white cDNA. (Chung et al., 1993) 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors.
Phenotypic class	courtship behavior defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)	pP{UAS-dap.L} (Lane et al., 1996)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{UAS-dap.L} (FlyBase, 1996-) UASdacapo (Delanoue et al., 2002) UAS-Dacapo (Wang et al., 2006, Remaud et al., 2008) UAS-dacapo (Brun et al., 2006) UAS-Dap (Audibert et al., 2005, Ninov et al., 2007, Remaud et al., 2008) UAS-dap (Berger et al., 2005, Duman-Scheel et al., 2004, Szuplewski et al., 2003, Han and Bodmer, 2003, Duman-Scheel et al., 2002, Legent et al., 2006, Delanoue et al., 2004) UAS dap (Shibutani et al., 2007) UAS-dap(II.3) (Zielke et al., 2006) UAS-decapo (van de Bor et al., 1999) unnamed (Gupta et al., 2008)
Secondary FlyBase IDs

References ( 20 )
Research paper	Gupta et al., 2008, Cell Cycle 7(15): 2401--2408 Cell cycle regulation by the pro-apoptotic gene Scotin. [FBrf0205659] Remaud et al., 2008, PLoS ONE 3(11): e3646 S-phase favours notch cell responsiveness in the Drosophila bristle lineage. [FBrf0206232] Ninov et al., 2007, Development 134(2): 367--379 Extrinsic and intrinsic mechanisms directing epithelial cell sheet replacement during Drosophila metamorphosis. [FBrf0194691] Shibutani et al., 2007, Development 134(3): 467--478 Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis. [FBrf0192129] Brun et al., 2006, Cell Death Differ. 13(10): 1752--1762 The myb-related gene stonewall induces both hyperplasia and cell death in Drosophila: rescue of fly lethality by coexpression of apoptosis inducers. [FBrf0193692] Legent et al., 2006, Genes Cells 11(8): 907--918 Cell cycle genes regulate vestigial and scalloped to ensure normal proliferation in the wing disc of Drosophila melanogaster. [FBrf0193006] Wang et al., 2006, Genes Dev. 20(24): 3453--3463 Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts. [FBrf0194325] Zielke et al., 2006, EMBO Rep. 7(12): 1266--1272 Molecular dissection of the APC/C inhibitor Rca1 shows a novel F-box-dependent function. [FBrf0193300] Audibert et al., 2005, Development 132(10): 2287--2297 Cell cycle diversity involves differential regulation of Cyclin E activity in the Drosophila bristle cell lineage. [FBrf0187449] Berger et al., 2005, Nat. Cell Biol. 7(1): 56--62 A critical role for Cyclin E in cell fate determination in the central nervous system of Drosophila melanogaster. [FBrf0184186] Delanoue et al., 2004, Cell Death Differ. 11(1): 110--122 The Drosophila wing differentiation factor Vestigial-Scalloped is required for cell proliferation and cell survival at the dorso-ventral boundary of the wing imaginal disc. [FBrf0167376] Duman-Scheel et al., 2004, Proc. Natl. Acad. Sci. U.S.A. 101(11): 3857--3862 Repression of dMyc expression by Wingless promotes Rbf-induced G1 arrest in the presumptive Drosophila wing margin. [FBrf0175090] Han and Bodmer, 2003, Development 130(13): 3039--3051 Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division. [FBrf0160590] Szuplewski et al., 2003, Development 130(16): 3651--3662 The Drosophila bZIP transcription factor Vrille is involved in hair and cell growth. [FBrf0160992] Delanoue et al., 2002, Genes Cells 7(12): 1255--1266 Interaction between apterous and early expression of vestigial in formation of the dorso-ventral compartments in the Drosophila wing disc. [FBrf0155789] Duman-Scheel et al., 2002, Nature 417(6886): 299--304 Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. [FBrf0149123] van de Bor et al., 1999, Cell Death Differ. 6(6): 557--564 Truncated products of the vestigial proliferation gene induce apoptosis. [FBrf0111532] Calvi et al., 1998, Genes Dev. 12(5): 734--744 Cell cycle control of chorion gene amplification. [FBrf0101877] Weiss et al., 1998, Curr. Biol. 8(4): 239--242 Continuous Cyclin E expression inhibits progression through endoreduplication cycles in Drosophila. [FBrf0100714] Lane et al., 1996, Cell 87(7): 1225--1235 Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. [FBrf0091107]