Recombinant construct P{GMR-hid}

General Information
Symbol	P{GMR-hid}	FlyBase ID	FBtp0001390
Feature type	transgenic_transposon	Created / Updated	1998-04-09/1998-06-08

Size		Expression data
Location-dependent role		Associated insertions	7 available
Molecular map
Description & Uses
Species	synthetic construct
Description	CV term Qualifiers & info Reference transposon P-element (Grether et al., 1995, Herz et al., 2006)
Uses	CV term Qualifiers & info Reference characterization W (Grether et al., 1995) apoptosis (Hay et al., 1995) + \| regulatory (Herz et al., 2006) w (Herz et al., 2006) GMR construct W (Grether et al., 1995)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Sequence
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference ectopic expression (Grether et al., 1995) selectable marker (Grether et al., 1995, Stowers, 1999.6.18)
Component Alleles
W^GMR.PG
Reference(s)	(Klarsfeld et al., 2004, Stowers et al., 2002, Wildonger et al., 2005, Zhou et al., 1999, Kanuka et al., 1999, Rodriguez Moncalvo and Campos, 2005, Verdu et al., 1999, Quinn et al., 2003, Ditzel et al., 2003, Mueller et al., 2005, Xu et al., 2005, Brenman et al., 2001, Rodriguez et al., 2002, Cook et al., 2003, Rawls and Wolff, 2003, Malpel et al., 2002, Lin et al., 2003, Tapon et al., 2002, Pfleger et al., 2007, Mirkovic et al., 2002, Rikhy et al., 2002, Bach et al., 2003, Wilson et al., 2002, Ryoo et al., 2002, Jia et al., 2003, Hays et al., 2002, Wing et al., 2002, Brumby and Richardson, 2003, Gottfried et al., 2004, Pantalacci et al., 2003, Shi and Skeath, 2004, Lee et al., 2004, Singh and Choi, 2003, Mason et al., 2003, Hong et al., 2003, Lisi et al., 2000, Meier et al., 2000, Hassan et al., 2000, Quinn et al., 2000, Tanenbaum et al., 2000, Taguchi et al., 2000, Rodriguez et al., 1999, Song et al., 2000, Goyal et al., 2000, Stowers and Schwarz, 1999, Busto et al., 1999, Bergmann et al., 1998, Stowers, 1999.6.18, Domingos et al., 2004, Lai et al., 2005, Rusconi et al., 2004, Overstreet et al., 2004, Pedraza et al., 2004, Harvey et al., 2001, Kurada and White, 1998, Bergmann et al., 1998, Rousset et al., 2001, Sawamoto et al., 1998, Jackson et al., 1998, Chen et al., 1998, Grether et al., 1995, Hay et al., 1995, Brennecke et al., 2003, Ryoo et al., 2002, Chew et al., 2004, Muro et al., 2006, Herz et al., 2006, Nairz et al., 2006, Huh et al., 2007, Hsu et al., 2004)
Molecular data	Construct: Expression of 3.9kb EcoRI fragment containing the W cDNA is driven by an eye-specific regulatory element, glass multimer reporter (GMR). (Grether et al., 1995)
Phenotypic class	visible (Rusconi et al., 2004, Stowers and Schwarz, 1999, Bergmann et al., 1998, Kurada and White, 1998, Wing et al., 2002, Brennecke et al., 2003, Taguchi et al., 2000, Ryoo et al., 2002, Hays et al., 2002, Rodriguez et al., 1999, Bach et al., 2003, Mueller et al., 2005, Harvey et al., 2001, Kanuka et al., 1999, Gottfried et al., 2004, Sawamoto et al., 1998, Grether et al., 1995, Wilson et al., 2002, Quinn et al., 2000, Ditzel et al., 2003, Pfleger et al., 2007, Huh et al., 2007) phototaxis behavior defective \| larval stage (Hassan et al., 2000) cell death defective (Bergmann et al., 1998, Lisi et al., 2000) visible \| dominant (Lisi et al., 2000) cell death increase (Kurada and White, 1998, Taguchi et al., 2000, Hays et al., 2002, Tapon et al., 2002, Jia et al., 2003, Lai et al., 2005, Rodriguez Moncalvo and Campos, 2005, Grether et al., 1995, Herz et al., 2006) visible \| somatic clone (Xu et al., 2005) neuroanatomy defective (Malpel et al., 2002, Rodriguez Moncalvo and Campos, 2005) behavior defective \| larval stage \| recessive (Busto et al., 1999) locomotor rhythm defective (Klarsfeld et al., 2004) locomotor behavior defective \| larval stage (Hassan et al., 2000)
Phenotype manifest in	ommatidium (Rusconi et al., 2004, Bergmann et al., 1998, Hays et al., 2002, Rodriguez et al., 1999, Gottfried et al., 2004, Shi and Skeath, 2004, Nairz et al., 2006) photoreceptor cell (Stowers and Schwarz, 1999, Rodriguez Moncalvo and Campos, 2005) larval Bolwig's organ (Hassan et al., 2000) eye (Meier et al., 2000, Bergmann et al., 1998, Lisi et al., 2000, Kurada and White, 1998, Wing et al., 2002, Song et al., 2000, Brennecke et al., 2003, Taguchi et al., 2000, Wildonger et al., 2005, Ryoo et al., 2002, Hays et al., 2002, Hay et al., 1995, Zhou et al., 1999, Tapon et al., 2002, Rodriguez et al., 1999, Bach et al., 2003, Mueller et al., 2005, Harvey et al., 2001, Kanuka et al., 1999, Gottfried et al., 2004, Quinn et al., 2003, Lai et al., 2005, Sawamoto et al., 1998, Grether et al., 1995, Wilson et al., 2002, Quinn et al., 2000, Ditzel et al., 2003, Muro et al., 2006, Herz et al., 2006, Fang et al., 2006, Pfleger et al., 2007, Huh et al., 2007) eye disc (Taguchi et al., 2000, Jia et al., 2003, Sawamoto et al., 1998, Rodriguez Moncalvo and Campos, 2005) eye \| somatic clone (Xu et al., 2005) larval lateral neuron (Malpel et al., 2002) Bolwig's nerve (Malpel et al., 2002) serotonin neuron (Rodriguez Moncalvo and Campos, 2005) interommatidial bristle (Nairz et al., 2006)
Other information
w^+mC
Reference(s)	(Grether et al., 1995, Stowers, 1999.6.18)
Molecular data	Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors. 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Minigene of the white cDNA. (Chung et al., 1993) Deletion of w^+mC 5' flanking sequences to position -305. (Qian and Pirrotta, 1995)
Phenotypic class	courtship defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^Sym.Scer\UAS, w^{a.Sym.Scer\UAS} (Giordano et al., 2002)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^Sym.Scer\UAS, w^{a.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
w⁺
Reference(s)	(Herz et al., 2006)
Molecular data
Phenotypic class
Phenotype manifest in
Other information
Expression Data
Reporter Expression
Stage Tissue/Position Reference
Additional Information
Statement Reference

Assay mode
Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)	pP{GMR-hid} (Grether et al., 1995)
descendant(s)
Comments
	construct_comment: See report for GMR. (Grether et al., 1995)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	FMR-Hid (Brumby and Richardson, 2003) GMR:Hid (Brennecke et al., 2003) GMR>hid (Singh and Choi, 2003) GMR-hid (Mueller et al., 2005, Xu et al., 2005, Lai et al., 2005, Overstreet et al., 2004, Domingos et al., 2004, Gottfried et al., 2004, Lee et al., 2004, Hong et al., 2003, Pantalacci et al., 2003, Mason et al., 2003, Bach et al., 2003, Jia et al., 2003, Ryoo et al., 2002, Quinn et al., 2003, Ditzel et al., 2003, Mirkovic et al., 2002, Tapon et al., 2002, Hays et al., 2002, Ryoo et al., 2002, Wilson et al., 2002, Rodriguez et al., 2002, Malpel et al., 2002, Brenman et al., 2001, Harvey et al., 2001, Quinn et al., 2000, Tanenbaum et al., 2000, Grether et al., 1995, Song et al., 2000, Taguchi et al., 2000, Goyal et al., 2000, Meier et al., 2000, Zhou et al., 1999, Kanuka et al., 1999, Sawamoto et al., 1998, Chew et al., 2004, Muro et al., 2006, Herz et al., 2006, Nairz et al., 2006, Pfleger et al., 2007, Klarsfeld et al., 2004) gmr-hid (Rusconi et al., 2004) GMR-Hid (Cook et al., 2003, Rikhy et al., 2002, Huh et al., 2007) GMRhid (Rawls and Wolff, 2003, Lisi et al., 2000) gmrhid (Verdu et al., 1999) GNR-hid (Stowers et al., 2002) P[GMR-hid] (Lin et al., 2003, Wing et al., 2002, Rodriguez et al., 1999) P[GMRhid] (Hsu et al., 2004) P{@w^+mC@ @W^GMR.PG@=@GMR-hid@} (FlyBase, 1996-) P{GMR-hid} (FlyBase, 1996-) pGMR-hid (Hassan et al., 2000, Stowers and Schwarz, 1999)
Secondary FlyBase IDs

References ( 83 )

Generate a list of	All references relating to this transgenic transposon ( 83 )

List References by type	Research paper ( 78 ) Review ( 2 ) Erratum ( 1 ) Personal communication to FlyBase ( 1 ) FlyBase analysis ( 1 )
Recent research papers ( 6 )
	Huh et al., 2007, J. Biol. Chem. 282(3): 2056--2068 The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers. [FBrf0192423] Pfleger et al., 2007, Fly 1(2): 95--105 Mutation of the gene encoding the ubiquitin activating enzyme Uba1 causes tissue overgrowth in Drosophila. [FBrf0200069] Fang et al., 2006, EMBO J. 25(11): 2735--2745 C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. [FBrf0192637] Herz et al., 2006, Development 133(10): 1871--1880 vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis. [FBrf0190294] Muro et al., 2006, Development 133(17): 3305--3315 The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. [FBrf0192459] Nairz et al., 2006, Dev. Biol. 291(2): 314--324 Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. [FBrf0190148] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2006 Show reviews ...