Recombinant construct P{UAS-arm.S10}

General Information
Symbol	P{UAS-arm.S10}	FlyBase ID	FBtp0001723
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	1 available
Molecular map
Recent Updates
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FB2013_03
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Pai et al., 1997)
Uses	CV term Qualifiers & info Reference binary system (targeted) arm (Pai et al., 1997) characterization arm (Pai et al., 1997)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Pai et al., 1997) chimeric gene (Pai et al., 1997) modified gene (Pai et al., 1997) molecular tag (Pai et al., 1997) selectable marker (Pai et al., 1997)
Component Alleles
Allele	arm^{S10.Scer\UAS.T:Hsap\MYC}
Reference(s)	(Takacs et al., 2008, O'Keefe et al., 1997, Hoffmans et al., 2005, Kaltschmidt et al., 2002, Brennan et al., 1999, Song and Xie, 2003, Gritzan et al., 1999, Marty et al., 2001, Piddini et al., 2005, Cox et al., 1999, Tolwinski et al., 2003, Angelats et al., 2002, Prasad et al., 2003, Yang et al., 2002, Price and Kalderon, 2002, Llimargas and Lawrence, 2001, Mueller et al., 2005, Kramps et al., 2002, Streit et al., 2002, Sudarsan et al., 2001, Takaesu et al., 2005, Alexandre and Vincent, 2003, Glise et al., 2002, Buratovich and Wilder, 2001, Wu and Cohen, 2002, Giraldez et al., 2002, Tolwinski and Wieschaus, 2004, Inaki et al., 2002, Jackson et al., 2002, Thompson et al., 2002, Ponzielli et al., 2002, Brumby and Richardson, 2003, Larsen et al., 2003, Cadigan et al., 2002, Adachi-Yamada and O'Connor, 2002, Akong et al., 2002, Bajpai et al., 2004, Chihara and Hayashi, 2000, Yan et al., 2004, Dichtel-Danjoy et al., 2009, Jaiswal et al., 2006, Thompson, 2004, Moreno and Basler, 2004, Takashima and Murakami, 2001, Halfon et al., 2000, Verheyen et al., 2001, Baeg et al., 2001, Freeman and Bienz, 2001, Hatini et al., 2000, Chang et al., 2008, Zeng et al., 2000, Waltzer et al., 2001, Yang et al., 2000, Llimargas, 2000, McEwen et al., 2000, Buratovich et al., 2000, San Martin and Bate, 2001, Yu et al., 1999, Alexandre et al., 1999, Helms et al., 1999, Erkner et al., 1999, Payre et al., 1999, Kopp et al., 1999, Garcia-Garcia et al., 1999, Von Ohlen and Hooper, 1999, Yu et al., 1998, Hatini et al., 2005, Gallet et al., 1999, Cox and Baylies, 2005, Han et al., 2005, Hacker et al., 1997, Morel and Arias, 2004, Hoffmans and Basler, 2004, Kouzmenko et al., 2004, Tolwinski and Wieschaus, 2001, Boube et al., 2001, Cadigan et al., 1998, Axelrod et al., 1998, Gallet et al., 1998, Loureiro et al., 2001, Rousset et al., 2001, Hatini and DiNardo, 2001, Steitz et al., 1998, Bilder and Scott, 1998, Kubota et al., 2003, Wernet et al., 2003, Pai et al., 1997, van de Wetering et al., 1997, Boyle et al., 1997, Stultz et al., 2006, Joshi et al., 2006, Estrada et al., 2006, Baena-Lopez et al., 2009, Seto and Bellen, 2006, Hayward et al., 2005, Olson et al., 2011, Uddin et al., 2011, Kiger et al., 2007, Avanesov et al., 2012, Casad et al., 2012, Shindo et al., 2008, Lee et al., 2009, Brás-Pereira and Casares, 2008, Lee et al., 2009, Gettings et al., 2010, Jones et al., 2010, Sinenko et al., 2009, Maqbool et al., 2006, Kleinschmit et al., 2010, Benchabane et al., 2011, Benchabane et al., 2011, Mirkovic et al., 2011, Bhambhani et al., 2011, Mirkovic et al., 2011, Chen and Verheyen, 2012, Pereira et al., 2006, Galindo et al., 2011, You et al., 2011)
Molecular data	A constitutively activated form of arm is expressed under the control of Scer\UAS regulatory sequences. (Boyle et al., 1997) Construct: A truncated arm protein, lacking amino acids 34 to 87 and tagged with T:Hsap\MYC, is expressed under the control of Scer\UAS regulatory sequences. (Pai et al., 1997) Expression of an arm gene carrying deletion of amino acids 34-87 is directed by Scer\UAS Scer\GAL4 binding sites. (van de Wetering et al., 1997)
Phenotypic class	size defective, with Scer\GAL4^nub-AC-62, Scer\GAL80^ts.αTub84B (Baena-Lopez et al., 2009) viable, with Scer\GAL4^pros.PMG (Akong et al., 2002) visible, with Scer\GAL4^bi.PU (Pereira et al., 2006) visible, with Scer\GAL4^bs-1348 (Verheyen et al., 2001) visible, with Scer\GAL4^Bx-MS1096 (Von Ohlen and Hooper, 1999) visible, with Scer\GAL4^dpp.blk1 (Kopp et al., 1999) visible, with Scer\GAL4^GF1 (Takacs et al., 2008) visible, with Scer\GAL4^GMR.PF (Bhambhani et al., 2011) visible, with Scer\GAL4^nub-AC-62, Scer\GAL80^ts.αTub84B (Baena-Lopez et al., 2009) visible, with Scer\GAL4^sd-SG29.1 (Brennan et al., 1999)
Phenotype manifest in	abdominal sternite bristle \| ectopic, with Scer\GAL4^GF1 (Takacs et al., 2008) abdominal ventral acute muscle 1 founder cell \| supernumerary, with Scer\GAL4^Mef2.PR (Cox and Baylies, 2005) abdominal ventral acute muscle 1 founder cell \| supernumerary, with Scer\GAL4^twi.PB (Cox and Baylies, 2005) abdominal ventral acute muscle 2 founder cell \| supernumerary, with Scer\GAL4^Mef2.PR (Cox and Baylies, 2005) abdominal ventral acute muscle 2 founder cell \| supernumerary, with Scer\GAL4^twi.PB (Cox and Baylies, 2005) abdominal ventral acute muscle 3 founder cell \| supernumerary, with Scer\GAL4^Mef2.PR (Cox and Baylies, 2005) abdominal ventral acute muscle 3 founder cell \| supernumerary, with Scer\GAL4^twi.PB (Cox and Baylies, 2005) abdominal ventral denticle belt, with Scer\GAL4^arm.PS (Jones et al., 2010) antennal disc, with Scer\GAL4^dpp.blk1 (Brás-Pereira and Casares, 2008) denticle, with Scer\GAL4^69B (Angelats et al., 2002) denticle, with Scer\GAL4^unspecified (Thompson, 2004) denticle belt, with Scer\GAL4^69B (Pai et al., 1997) denticle belt, with Scer\GAL4^arm.PS (Thompson et al., 2002) denticle belt, with Scer\GAL4^e22c (Cox et al., 1999, Pai et al., 1997, Payre et al., 1999) denticle belt, with Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} (Tolwinski and Wieschaus, 2001) denticle row 1, with Scer\GAL4^en-e16E (Pai et al., 1997, Takaesu et al., 2005) direct flight muscle, with Scer\GAL4¹¹⁵¹ (Sudarsan et al., 2001) dorsal denticle, with Scer\GAL4^arm.PS (Hatini et al., 2000) dorsal fine hair \| ectopic, with Scer\GAL4^arm.PS (Hatini et al., 2000) dorsal fine hair \| ectopic, with Scer\GAL4^ptc-559.1 (Hatini et al., 2000) dorsal hair, with Scer\GAL4^{arm.T:Hsim\VP16} (McEwen et al., 2000) dorsal margin photoreceptor \| ectopic, with Scer\GAL4^GMR.long (Wernet et al., 2003) dorsal thick hair, with Scer\GAL4^arm.PS (Hatini et al., 2000) embryonic/first instar larval cuticle, with Scer\GAL4^69B (Gallet et al., 1998) embryonic/first instar larval cuticle, with Scer\GAL4^arm.PS (Tolwinski and Wieschaus, 2004) embryonic/first instar larval cuticle, with Scer\GAL4^e22c (Cox et al., 1999, van de Wetering et al., 1997) embryonic/first instar larval cuticle, with Scer\GAL4^hs.PB (Gallet et al., 1998) embryonic/first instar larval cuticle, with Scer\GAL4^unspecified (Thompson, 2004) embryonic/first instar larval cuticle, with Scer\GAL4^αTub84B.PK (Kramps et al., 2002) embryonic/first instar larval cuticle & denticle, with Scer\GAL4^da.G32 (Hoffmans and Basler, 2004) embryonic/first instar larval cuticle & denticle belt, with Scer\GAL4^da.G32 (Hoffmans et al., 2005) embryonic/first instar larval cuticle \| dorsal, with Scer\GAL4^{arm.T:Hsim\VP16} (McEwen et al., 2000) embryonic/larval dorsal trunk, with Scer\GAL4^btl.PS (Llimargas, 2000, Loureiro et al., 2001) embryonic/larval visceral branch, with Scer\GAL4^btl.PS (Llimargas, 2000, Chihara and Hayashi, 2000) embryonic epidermis, with Scer\GAL4^e22c (Payre et al., 1999) embryonic epidermis \| dorsal, with Scer\GAL4^arm.PS (Hatini et al., 2000) embryonic epidermis \| dorsal, with Scer\GAL4^{arm.T:Hsim\VP16} (McEwen et al., 2000) embryonic epidermis \| dorsal, with Scer\GAL4^ptc-559.1 (Hatini et al., 2000) eye, with Scer\GAL4^GMR.PF (Freeman and Bienz, 2001, Bhambhani et al., 2011) eye, with Scer\GAL4^hs.2sev (Jackson et al., 2002) eye photoreceptor cell, with Scer\GAL4^GMR.long (Benchabane et al., 2011) eye photoreceptor cell, with Scer\GAL4^hs.2sev (Mirkovic et al., 2011) interfollicle cell \| supernumerary \| heat sensitive, with Scer\GAL4^hs.PB (Song and Xie, 2003) interommatidial bristle, with Scer\GAL4^GMR.PF (Rousset et al., 2001) interommatidial bristle, with Scer\GAL4^hs.2sev (Jackson et al., 2002) lymph gland derived hemocyte \| third instar larval stage, with Scer\GAL4^dome-PG14 (Sinenko et al., 2009) midgut constriction 1, with Scer\GAL4^how-24B (Yu et al., 1999) midgut constriction 2, with Scer\GAL4^how-24B (Steitz et al., 1998) morphogenetic furrow, with Scer\GAL4^dpp.blk1 (Cadigan et al., 2002) ommatidium, with Scer\GAL4^GMR.PF (Rousset et al., 2001) ommatidium, with Scer\GAL4^hs.2sev (Jackson et al., 2002) pleural membrane, with Scer\GAL4^GF1 (Takacs et al., 2008) pleurum, with Scer\GAL4^dpp.blk1 (Kopp et al., 1999) sensory mother cell & dorsal mesothoracic disc \| ectopic, with Scer\GAL4^sd-SG29.1 (Brennan et al., 1999) sternite, with Scer\GAL4^GF1 (Takacs et al., 2008) T1 beard, with Scer\GAL4^69B (Angelats et al., 2002) wing, with Scer\GAL4^30A (Kiger et al., 2007) wing, with Scer\GAL4^bbg-C96 (Helms et al., 1999) wing, with Scer\GAL4^bi.PU (Pereira et al., 2006) wing, with Scer\GAL4^Bx-MS1096 (Von Ohlen and Hooper, 1999) wing, with Scer\GAL4^nub-AC-62, Scer\GAL80^ts.αTub84B (Baena-Lopez et al., 2009) wing disc, with Scer\GAL4^Dll-md23 (Kubota et al., 2003) wing disc, with Scer\GAL4^dpp.blk1 (Brennan et al., 1999, Hayward et al., 2005) wing disc, with Scer\GAL4^sd-SG29.1 (Giraldez et al., 2002) wing disc \| anterior compartment, with Scer\GAL4^sd-SG29.1 (Brennan et al., 1999) wing hair, with Scer\GAL4^nub-AC-62, Scer\GAL80^ts.αTub84B (Baena-Lopez et al., 2009) wing hinge, with Scer\GAL4^sd-SG29.1 (Brennan et al., 1999) wing margin bristle, with Scer\GAL4^Bx-MS1096 (Von Ohlen and Hooper, 1999) wing margin bristle \| ectopic, with Scer\GAL4⁴⁰⁵ (Bajpai et al., 2004) wing margin bristle \| ectopic, with Scer\GAL4^bbg-C96 (Helms et al., 1999) wing margin bristle \| ectopic, with Scer\GAL4^sd-SG29.1 (Brennan et al., 1999) wing margin bristle \| ectopic, with Scer\GAL4^vg.PM (Bajpai et al., 2004) wing vein \| ectopic, with Scer\GAL4^bs-1348 (Verheyen et al., 2001, Lee et al., 2009)
Other information

Allele	w^+mC
Reference(s)	(Pai et al., 1997)
Molecular data	Minigene of the white cDNA. (Chung et al., 1993) 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors.
Phenotypic class	courtship behavior defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference Functions normally at adherens junctions; shows ectopic accumulation in cytoplasm and nucleus. (Pai et al., 1997)

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)	pP{UAST} (Pai et al., 1997)
descendant(s)
Comments
	construct_comment: Progenitors are those of the plasmid, pP{UAS-arm.S10}. (Pai et al., 1997) report comment: Encodes a modified form of ARM protein with increased stability and altered subcellular distribution: functions normally at adherens junctions, but also accumulates in the cytoplasm and nucleus. (Pai et al., 1997)
Stocks Listed in FlyBase ( 2 )
Bloomington	4782 P{UAS-arm.S10}C, y¹ w¹¹¹⁸
Kyoto	107877 P{UAS-arm.S10}C, y¹ w¹¹¹⁸
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	activated Armadillo (Maqbool et al., 2006) arm^S10 (Gettings et al., 2010) Arm^S10 (Avanesov et al., 2012, Chen and Verheyen, 2012) arm^S10-wt (Hoffmans et al., 2005, Hoffmans and Basler, 2004) Armadillo^s10 (Hayward et al., 2005) Armadillo^S10 (Avanesov et al., 2012) Arm-S10 (Cox et al., 1999) ArmS10 (Kiger et al., 2007) P[UAS-arm^S10] (Rousset et al., 2001) P[UAS-arm^SC10] (Cadigan et al., 2002) P{arm.S10} (Brás-Pereira and Casares, 2008) P{UAS-arm.S10} (FlyBase, 1996-, Casad et al., 2012) P^{UAS-arm<up>S10}</up> (Chang et al., 2008) UAS.ArmS10 (Thompson et al., 2002) UAS.CA-Arm (Takaesu et al., 2005) UAS.S10 (Yu et al., 1999, Yu et al., 1998) UAS-arm (Adachi-Yamada and O'Connor, 2002) UAS-Arm (Helms et al., 1999) UAS-arm.S10 (Jackson et al., 2002) UASarm* (Llimargas and Lawrence, 2001, Llimargas, 2000, Brennan et al., 1999) UAS-Arm* (Dichtel-Danjoy et al., 2009, Bhambhani et al., 2011, Olson et al., 2011) UAS-arm* (Bhambhani et al., 2011) UAS-Arm*[S10] (Tolwinski and Wieschaus, 2004, Tolwinski et al., 2003) UAS-arm^act (Han et al., 2005, Baeg et al., 2001) UAS-Arm^Act (Hatini et al., 2000) UAS-Arm^act (You et al., 2011) UAS-Arm^S10 (Hatini et al., 2005, Morel and Arias, 2004, Akong et al., 2002, Glise et al., 2002, Loureiro et al., 2001, Hatini et al., 2000, Waltzer et al., 2001, Zeng et al., 2000, Baena-Lopez et al., 2009, Seto and Bellen, 2006, Dichtel-Danjoy et al., 2009, Kleinschmit et al., 2010) UAS-arm^S10 (Cox and Baylies, 2005, Bajpai et al., 2004, Moreno and Basler, 2004, Brumby and Richardson, 2003, Yan et al., 2004, Larsen et al., 2003, Song and Xie, 2003, Prasad et al., 2003, Wu and Cohen, 2002, Inaki et al., 2002, Giraldez et al., 2002, Price and Kalderon, 2002, Yang et al., 2002, Sudarsan et al., 2001, Takashima and Murakami, 2001, Chihara and Hayashi, 2000, McEwen et al., 2000, Alexandre et al., 1999, Garcia-Garcia et al., 1999, Kopp et al., 1999, Joshi et al., 2006, Benchabane et al., 2011, Benchabane et al., 2011, Lee et al., 2009, Jaiswal et al., 2006, Lee et al., 2009, Jones et al., 2010, Sinenko et al., 2009, Avanesov et al., 2012, Shindo et al., 2008, Galindo et al., 2011) UAS-Arm^s10 (Alexandre and Vincent, 2003, Liu et al., 2003, Verheyen et al., 2001) UASarm^S10 (Buratovich and Wilder, 2001, Buratovich et al., 2000) UAS-arm^s10 (Halfon et al., 2000, Estrada et al., 2006, Takacs et al., 2008) UASArm^S10 (Yang et al., 2000) UAS arm^s10 (Stultz et al., 2006) UAS-arm^S10C (Kaltschmidt et al., 2002) UASarm^S10C (San Martin and Bate, 2001) UAS-Arm^S10C (Helms et al., 1999) UAS-armadillo^act (Mueller et al., 2005) UAS-armadillo^S10 (Piddini et al., 2005) UAS-Armadillo S10 (Ponzielli et al., 2002) UAS-armadillo S10 (Kiger et al., 2007) UAS-ArmS10 (Kouzmenko et al., 2004, Wernet et al., 2003, Hatini and DiNardo, 2001, Payre et al., 1999, Mirkovic et al., 2011, Mirkovic et al., 2011, Pereira et al., 2006) UAS ArmS10 (Thompson, 2004) UAS-armS10 (Kubota et al., 2003, Streit et al., 2002, Marty et al., 2001, Boube et al., 2001, Llimargas, 2000, Brás-Pereira and Casares, 2008, Uddin et al., 2011, Casad et al., 2012) UAS-Arm-S10 (Gritzan et al., 1999) UASArmS10c (Erkner et al., 1999, Gallet et al., 1999) UASD-armS10C (Angelats et al., 2002) UAS-S10 (Tolwinski and Wieschaus, 2001)
Secondary FlyBase IDs

References ( 119 )

Generate a list of	All references relating to this transgenic transposon ( 119 )

List References by type	Research paper ( 116 ) Supplementary material ( 3 )
Recent research papers ( 10 )
	Avanesov et al., 2012, PLoS Genet. 8(2): e1002503 The Role of Glypicans in Wnt Inhibitory Factor-1 Activity and the Structural Basis of Wif1's Effects on Wnt and Hedgehog Signaling. [FBrf0217590] Casad et al., 2012, Mol. Genet. Genomics 287(4): 351--360 Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy. [FBrf0217871] Chen and Verheyen, 2012, Curr. Biol. 22(17): 1582--1586 Homeodomain-interacting protein kinase regulates yorkie activity to promote tissue growth. [FBrf0219448] Benchabane et al., 2011, EMBO J. 30(8): 1444--1458 Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity. [FBrf0213544] Bhambhani et al., 2011, EMBO J. 30(10): 2031--2043 The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets. [FBrf0213805] Galindo et al., 2011, Dev. Biol. 353(2): 396--410 Control of Distal-less expression in the Drosophila appendages by functional 3' enhancers. [FBrf0213529] Mirkovic et al., 2011, Nat. Struct. Mol. Biol. 18(6): 665--672 Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin. [FBrf0213849] Olson et al., 2011, EMBO Rep. 12(10): 1047--1054 Yan, an ETS-domain transcription factor, negatively modulates the Wingless pathway in the Drosophila eye. [FBrf0216277] Uddin et al., 2011, Int. J. Dev. Biol. 55(10-11-12): 945--952 The drumstick gene acts cell-non-autonomously and triggers specification of the small intestine in the Drosophila hindgut. [FBrf0217187] You et al., 2011, Dev. Dyn. 240(3): 640--648 Sulfated is a negative feedback regulator of wingless in Drosophila. [FBrf0213052] Show all research papers ...