Recombinant construct P{sev-phyl}

General Information
Symbol	P{sev-phyl}	FlyBase ID	FBtp0004956
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	0 available
Molecular map
Recent Updates
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Dickson et al., 1995)
Uses	CV term Qualifiers & info Reference characterization phyl (Dickson et al., 1995) heat-shock construct phyl (Dickson et al., 1995)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference inducible promoter (Dickson et al., 1995) selectable marker (Dickson et al., 1995)
Component Alleles
Allele	phyl^hs.sev
Reference(s)	(Nagaraj and Banerjee, 2009, Dickson et al., 1995, Tang et al., 2001, Maixner et al., 1998, Li et al., 1997, Tang et al., 1997, Chang and Rubin, 1997, Baril and Therrien, 2006)
Molecular data	Construct: phyl cDNA is expressed under the transcriptional control of an Hsp70 promoter and one copy of the sev enhancer. (Dickson et al., 1995)
Phenotypic class	visible (Tang et al., 1997)
Phenotype manifest in	cone cell \| precursor (Dickson et al., 1995) eye (Tang et al., 1997, Dickson et al., 1995, Baril and Therrien, 2006) photoreceptor cell R1 (Nagaraj and Banerjee, 2009) photoreceptor cell R6 (Nagaraj and Banerjee, 2009) photoreceptor cell R7 (Dickson et al., 1995) photoreceptor cell R7 \| supernumerary (Baril and Therrien, 2006)
Other information

Allele	w^+mW.hs
Reference(s)	(Dickson et al., 1995)
Molecular data	A mini-w gene is expressed under the control of an Hsp70 promoter. (Heinrich et al., 1993) w gene expression is under the influence of FLIP recombinase. (Golic and Lindquist, 1989) Expression of a fragment of w genomic DNA with a 2.2kb deletion of 3' flanking sequences and a reduction in the size of the largest intron to 356bp is driven by a 388bp fragment of an Hsp70 gene. (Klemenz et al., 1987) Construct: A 'mini-white' gene constructed by deletion of the XbaI-HindII fragment from the long 5' intron. Carried by the W6 and W8 series of vectors.
Phenotypic class	suppressor of variegation, with Su(var)205⁵⁰² (Ahmad and Golic, 1996)
Phenotype manifest in	pigment cell (Kurkulos et al., 1994, Golic and Lindquist, 1989)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{sev-phyl} (FlyBase, 1996-) sE-phyl (Tang et al., 2001, Maixner et al., 1998)
Secondary FlyBase IDs

References ( 8 )
Research paper	Nagaraj and Banerjee, 2009, EMBO J. 28(4): 337--346 Regulation of Notch and Wingless signalling by phyllopod, a transcriptional target of the EGFR pathway. [FBrf0206749] Baril and Therrien, 2006, Dev. Biol. 294(1): 232--245 Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila. [FBrf0190087] Tang et al., 2001, Development 128(5): 801--813 Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian. [FBrf0134581] Maixner et al., 1998, Dev. Genet. 23(4): 347--361 A screen for mutations that prevent lethality caused by expression of activated Sevenless and Ras1 in the Drosophila embryo. [FBrf0105879] Chang and Rubin, 1997, Genes Dev. 11(9): 1132--1139 14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila. [FBrf0093395] Li et al., 1997, Cell 90(3): 469--478 Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor tramtrack. [FBrf0098298] Tang et al., 1997, Cell 90(3): 459--467 PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. [FBrf0098364] Dickson et al., 1995, Cell 80(3): 453--462 Control of Drosophila photoreceptor cell fates by phyllopod, a novel nuclear protein acting downstream of the Raf kinase. [FBrf0079990]