Recombinant construct P{hsp(sE)-poxn}

General Information
Symbol	P{hsp(sE)-poxn}	FlyBase ID	FBtp0005069
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	0 available
Molecular map
Recent Updates
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Dambly-Chaudiere et al., 1992)
Uses	CV term Qualifiers & info Reference characterization Poxn (Dambly-Chaudiere et al., 1992) heat-shock construct Poxn (Dambly-Chaudiere et al., 1992)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference inducible promoter (Dambly-Chaudiere et al., 1992) selectable marker (Dambly-Chaudiere et al., 1992)
Component Alleles
Allele	Poxn^hs.sev
Reference(s)	(Dambly-Chaudiere et al., 1992, Jiao et al., 2001, del Alamo et al., 2002, Nottebohm et al., 1994, Zeidler et al., 1996, Gautier et al., 1997)
Molecular data	Construct: P4c6 Poxn cDNA expression is driven by an XbaI-KpnI fragment of the first 95bp of Hsp70 leader and 250bp of Hsp70 upstream sequence and a 1.2kb sev enhancer fragment. Transcription is terminated by a 0.8kb tubulin fragment. (Dambly-Chaudiere et al., 1992)
Phenotypic class	lethal \| recessive (Vervoort et al., 1995) visible (Jiao et al., 2001)
Phenotype manifest in	chemosensory sensory organ \| adult stage \| ectopic (Gautier et al., 1997) chemosensory sensory organ \| ectopic (del Alamo et al., 2002) chemosensory sensory organ \| ectopic \| larval stage (Gautier et al., 1997) chordotonal organ (Vervoort et al., 1995) cone cell (Jiao et al., 2001) external sensory organ (Vervoort et al., 1995) eye (Zeidler et al., 1996, Jiao et al., 2001) Kolbchen \| embryonic stage (Dambly-Chaudiere et al., 1992) mechanosensory sensory organ (del Alamo et al., 2002) mechanosensory sensory organ & tibia & adult (Nottebohm et al., 1994) mechanosensory sensory organ & tibia & neuron & adult (Nottebohm et al., 1994) ommatidium (Jiao et al., 2001)
Other information

Allele	w^+mW.hs
Reference(s)	(Dambly-Chaudiere et al., 1992)
Molecular data	A mini-w gene is expressed under the control of an Hsp70 promoter. (Heinrich et al., 1993) w gene expression is under the influence of FLIP recombinase. (Golic and Lindquist, 1989) Expression of a fragment of w genomic DNA with a 2.2kb deletion of 3' flanking sequences and a reduction in the size of the largest intron to 356bp is driven by a 388bp fragment of an Hsp70 gene. (Klemenz et al., 1987) Construct: A 'mini-white' gene constructed by deletion of the XbaI-HindII fragment from the long 5' intron. Carried by the W6 and W8 series of vectors.
Phenotypic class	suppressor of variegation, with Su(var)205⁵⁰² (Ahmad and Golic, 1996)
Phenotype manifest in	pigment cell (Kurkulos et al., 1994, Golic and Lindquist, 1989)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	hsp70-poxn (del Alamo et al., 2002) P{hsp(sE)-poxn} (FlyBase, 1996-) sev-Poxn (Jiao et al., 2001)
Secondary FlyBase IDs

References ( 6 )
Research paper	del Alamo et al., 2002, Development 129(8): 1975--1982 Spitz/EGFr signalling via the Ras/MAPK pathway mediates the induction of bract cells in Drosophila legs. [FBrf0146986] Jiao et al., 2001, Development 128(17): 3307--3319 Headless flies generated by developmental pathway interference. [FBrf0138373] Gautier et al., 1997, Gene 191(1): 15--21 tap, a Drosophila bHLH gene expressed in chemosensory organs. [FBrf0094752] Zeidler et al., 1996, Genes Dev. 10(1): 50--59 Drosophila TFIIA-S is up-regulated and required during Ras-mediated photoreceptor determination. [FBrf0086204] Nottebohm et al., 1994, Neuron 12(1): 25--34 The gene poxn controls different steps of the formation of chemosensory organs in Drosophila. [FBrf0068609] Dambly-Chaudiere et al., 1992, Cell 69(1): 159--172 The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila. [FBrf0055546]