Recombinant construct P{GMRp21^B}

General Information
Symbol	P{GMRp21^B}	FlyBase ID	FBtp0005370
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	0 available
Molecular map
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (de Nooij and Hariharan, 1995)
Uses	CV term Qualifiers & info Reference characterization GMR (de Nooij and Hariharan, 1995)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference
Component Alleles
Allele	Hsap\CDKN1A^GMR.PH
Reference(s)	(Quinn et al., 2004, Shi et al., 2003, Lisi et al., 2000, Baker and Yu, 2001, Staehling-Hampton et al., 1999, Ahmad and Golic, 1999, Du and Dyson, 1999, Boulton et al., 2000, Thomer et al., 2004, Secombe et al., 1998, de Nooij and Hariharan, 1995, Flores et al., 1998, Fan and Ready, 1997, Morris et al., 2006, Schneiderman et al., 2010, Fan et al., 2010)
Molecular data	Construct: Hsap\CDKN1A cDNA is expressed from a glass multimer reporter and an Hsp70 TATA box. (de Nooij and Hariharan, 1995)
Phenotypic class	visible (Secombe et al., 1998, Staehling-Hampton et al., 1999, Du and Dyson, 1999, Fan et al., 2010)
Phenotype manifest in	eye (Quinn et al., 2004, Secombe et al., 1998, Staehling-Hampton et al., 1999, Du and Dyson, 1999, Fan et al., 2010) eye disc (Staehling-Hampton et al., 1999) interommatidial bristle (de Nooij and Hariharan, 1995) ommatidium (Quinn et al., 2004, Staehling-Hampton et al., 1999, de Nooij and Hariharan, 1995) pigment cell (de Nooij and Hariharan, 1995)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	GMR:p21 (Thomer et al., 2004) GMR-p21 (Quinn et al., 2004, Staehling-Hampton et al., 1999, Morris et al., 2006, Schneiderman et al., 2010, Fan et al., 2010) GMRp21 (Shi et al., 2003, Lisi et al., 2000) GMR-p21^CIP1/WAF1 (Baker and Yu, 2001) P[GMR-p21] (Ahmad and Golic, 1999) P{GMRp21^B} (FlyBase, 1996-)
Secondary FlyBase IDs

References ( 16 )
Research paper	Fan et al., 2010, Cell Death Differ. 17(6): 912--921 Dual roles of Drosophila p53 in cell death and cell differentiation. [FBrf0210741] Schneiderman et al., 2010, PLoS Genet. 6(9): e1001095 Perturbation Analysis of Heterochromatin-Mediated Gene Silencing and Somatic Inheritance. [FBrf0211786] Morris et al., 2006, PLoS Genet. 2(11): e147 Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. [FBrf0194141] Quinn et al., 2004, Development 131(6): 1411--1423 Drosophila Hfp negatively regulates dmyc and stg to inhibit cell proliferation. [FBrf0174559] Thomer et al., 2004, Development 131(19): 4807--4818 Drosophila double-parked is sufficient to induce re-replication during development and is regulated by cyclin E/CDK2. [FBrf0180151] Shi et al., 2003, Genetics 165(4): 1869--1879 The pineapple eye gene is required for survival of Drosophila imaginal disc cells. [FBrf0167647] Baker and Yu, 2001, Cell 104(5): 699--708 The Egf receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye. [FBrf0134491] Boulton et al., 2000, EMBO J. 19(20): 5376--5386 A role for ebi in neuronal cell cycle control. [FBrf0131258] Lisi et al., 2000, Genetics 154(2): 669--678 Diverse domains of THREAD/DIAP1 are required to inhibit apoptosis induced by REAPER and HID in Drosophila. [FBrf0125418] Ahmad and Golic, 1999, Genetics 151(3): 1041--1051 Telomere loss in somatic cells of Drosophila causes cell cycle arrest and apoptosis. [FBrf0107578] Du and Dyson, 1999, EMBO J. 18(4): 916--925 The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis. [FBrf0106433] Staehling-Hampton et al., 1999, Genetics 153(1): 275--287 A genetic screen for modifiers of E2F in Drosophila melanogaster. [FBrf0111491] Flores et al., 1998, Development 125(18): 3681--3687 Lozenge is expressed in pluripotent precursor cells and patterns multiple cell types in the Drosophila eye through the control of cell-specific transcription factors. [FBrf0104748] Secombe et al., 1998, Genetics 149(4): 1867--1882 Analysis of a Drosophila cyclin E hypomorphic mutation suggests a novel role for cyclin E in cell proliferation control during eye imaginal disc development. [FBrf0103367] Fan and Ready, 1997, Development 124(8): 1497--1507 Glued participates in distinct microtubule-based activities in Drosophila eye development. [FBrf0093094] de Nooij and Hariharan, 1995, Science 270(5238): 983--985 Uncoupling cell fate determination from patterned cell division in the Drosophila eye. [FBrf0084543]

Recombinant construct P{GMRp21B}

Recombinant construct P{GMRp21^B}