Recombinant construct P{sevhs-csw^CS}

General Information
Symbol	P{sevhs-csw^CS}	FlyBase ID	FBtp0006292
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	1 available
Molecular map
Recent Updates
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Herbst et al., 1996)
Uses	CV term Qualifiers & info Reference characterization csw (Herbst et al., 1996) heat-shock construct csw (Herbst et al., 1996)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference inducible promoter (Herbst et al., 1996) selectable marker (Allard et al., 1998)
Component Alleles
Allele	csw^CS.hs.2sev
Reference(s)	(Herbst et al., 1999, Smith et al., 2002, Herbst et al., 1996, Allard et al., 1998, Jarvis et al., 2006)
Molecular data	Construct: Amino acid replacement: C583S. sev enhancers and an Hsp70 promoter drive expression of csw. (Allard et al., 1998)
Phenotypic class	increased cell death (Smith et al., 2002) visible (Herbst et al., 1996, Smith et al., 2002) visible \| dominant (Allard et al., 1998)
Phenotype manifest in	eye disc (Smith et al., 2002) eye photoreceptor cell (Allard et al., 1998, Smith et al., 2002) ommatidium (Allard et al., 1998, Smith et al., 2002) outer photoreceptor cell (Jarvis et al., 2006) photoreceptor cell R3 (Herbst et al., 1996, Allard et al., 1998) photoreceptor cell R4 (Herbst et al., 1996, Allard et al., 1998) photoreceptor cell R7 (Herbst et al., 1996, Allard et al., 1998, Smith et al., 2002)
Other information

Allele	w^+*
Reference(s)	(Allard et al., 1998)
Molecular data	Construct: Large intron is removed. (Jack et al., 1991)
Phenotypic class
Phenotype manifest in
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	P[sE-csw^CS] (Herbst et al., 1999) P[sevhs-csw^CS] (Smith et al., 2002) P{sevhs-csw^CS} (FlyBase, 1996-) SE-csw^C583S (Jarvis et al., 2006) sE-csw^CS (Herbst et al., 1999)
Secondary FlyBase IDs

References ( 5 )
Research paper	Jarvis et al., 2006, Development 133(6): 1133--1142 Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases. [FBrf0190302] Smith et al., 2002, Development 129(1): 71--82 MASK, a large ankyrin repeat and KH domain-containing protein involved in Drosophila receptor tyrosine kinase signaling. [FBrf0141508] Herbst et al., 1999, EMBO J. 18(24): 6950--6961 Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the sevenless receptor tyrosine kinase. [FBrf0123046] Allard et al., 1998, J. Biol. Chem. 273(21): 13129--13135 Mutational analysis of the SRC homology 2 domain protein-tyrosine phosphatase Corkscrew. [FBrf0102661] Herbst et al., 1996, Cell 85(6): 899--909 Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling. [FBrf0088202]

Recombinant construct P{sevhs-cswCS}

Recombinant construct P{sevhs-csw^CS}