Recombinant construct P{Dp110^D954A}

General Information
Symbol	P{Dp110^D954A}	FlyBase ID	FBtp0007481
Feature type	transgenic_transposon	Created / Updated	1999-09-22/1999-09-22

Size		Expression data
Location-dependent role		Associated insertions	0 available
Molecular map
Description & Uses
Species	synthetic construct
Description	CV term Qualifiers & info Reference transposon P-element (Leevers et al., 1996)
Uses	CV term Qualifiers & info Reference binary system (targeted) Pi3K92E (Leevers et al., 1996) characterization Pi3K92E (Leevers et al., 1996)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Sequence
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Leevers et al., 1996) molecular tag (Leevers et al., 1996)
Component Alleles
Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}
Reference(s)	(Wood et al., 2006, Yang et al., 2005, Caldwell et al., 2005, Goberdhan et al., 1999, Coelho et al., 2005, Raisin et al., 2003, Colombani et al., 2005, Coelho et al., 2005, Kramer et al., 2003, Wu et al., 2005, Britton et al., 2002, Colombani et al., 2005, Yang, 2005, Walker et al., 2006, Fulga and Rorth, 2002, Resino and Garcia-Bellido, 2004, Brumby and Richardson, 2003, Duchek and Rorth, 2001, Bruckner et al., 2004, Teleman and Cohen, 2000, Gao et al., 2000, Weinkove et al., 1999, Reiling and Hafen, 2004, Rusten et al., 2004, Miron et al., 2001, Cho et al., 2001, Junger et al., 2003, Leevers et al., 1996, Colombani et al., 2003, Goberdhan et al., 2005, Mikeladze-Dvali et al., 2005, Betschinger et al., 2006, Herranz et al., 2006, Bruckner et al., 2004)
Molecular data	Construct: Amino acid replacement: D954A. Residue in the putative ATP binding site. (Leevers et al., 1996)
Phenotypic class	reduced cell size, with Scer\GAL4^Bx-MS1096 (Gao et al., 2000) visible, with Scer\GAL4^Bx-MS1096 (Goberdhan et al., 1999, Bohni et al., 1999, Coelho et al., 2005) reduced cell number, with Scer\GAL4^GMR.PF (Kramer et al., 2003) reduced cell size, with Scer\GAL4^GMR.PF (Kramer et al., 2003) visible, with Scer\GAL4^GMR.PF (Junger et al., 2003) reduced cell size, with Scer\GAL4^ap-md544 (Resino and Garcia-Bellido, 2004) reduced cell size, with Scer\GAL4^dpp.blk1 (Resino and Garcia-Bellido, 2004) reduced cell number, with Scer\GAL4^dpp.blk1 (Resino and Garcia-Bellido, 2004) visible, with Scer\GAL4^dpp.blk1 (Resino and Garcia-Bellido, 2004, Miron et al., 2001, Goberdhan et al., 1999) size defective \| cell autonomous, with Scer\GAL4^dpp.blk1 (Resino and Garcia-Bellido, 2004) size defective \| cell non-autonomous, with Scer\GAL4^dpp.blk1 (Resino and Garcia-Bellido, 2004) large body \| adult stage, with Scer\GAL4^amn-c651 (Caldwell et al., 2005) large body \| pupal stage, with Scer\GAL4^amn-c651 (Caldwell et al., 2005) cell size defective, with Scer\GAL4^amn-c651 (Caldwell et al., 2005) developmental rate defective \| third instar larval stage, with Scer\GAL4^amn-c651 (Caldwell et al., 2005) large body \| pupal stage, with Scer\GAL4^amn-X8 (Caldwell et al., 2005) developmental rate defective \| third instar larval stage, with Scer\GAL4^amn-X8 (Caldwell et al., 2005) large body, with Scer\GAL4^P0206 (Colombani et al., 2005) increased cell number, with Scer\GAL4^P0206 (Colombani et al., 2005) developmental rate defective, with Scer\GAL4^P0206 (Colombani et al., 2005) wound healing defective, with Scer\GAL4^crq.PO (Wood et al., 2006)
Phenotype manifest in	1st posterior cell, with Scer\GAL4^ptc-559.1 (Cho et al., 2001) wing, with Scer\GAL4^Bx-MS1096 (Coelho et al., 2005, Gao et al., 2000, Goberdhan et al., 1999, Bohni et al., 1999, Coelho et al., 2005) eye, with Scer\GAL4^Bx-MS1096 (Bohni et al., 1999) eye, with Scer\GAL4^GMR.PF (Junger et al., 2003, Leevers et al., 1996) ommatidium, with Scer\GAL4^GMR.PF (Leevers et al., 1996) chaeta, with Scer\GAL4^ap-md544 (Resino and Garcia-Bellido, 2004) mesothoracic tergum, with Scer\GAL4^ap-md544 (Resino and Garcia-Bellido, 2004) 1st posterior cell, with Scer\GAL4^dpp.blk1 (Miron et al., 2001) wing, with Scer\GAL4^dpp.blk1 (Goberdhan et al., 1999, Leevers et al., 1996) wing & cell, with Scer\GAL4^dpp.blk1 (Goberdhan et al., 1999) prothoracic gland, with Scer\GAL4^amn-c651 (Caldwell et al., 2005) dorsal mesothoracic disc \| posterior compartment, with Scer\GAL4^en-e16E (Teleman and Cohen, 2000, Weinkove et al., 1999) imaginal disc & cell, with Scer\GAL4^Act5C.PP (Weinkove et al., 1999) wing, with Scer\GAL4^P0206 (Colombani et al., 2005) eye, with Scer\GAL4^P0206 (Colombani et al., 2005) germ band, with Scer\GAL4^Kr.PM (Herranz et al., 2006)
Other information
Expression Data
Reporter Expression
Stage Tissue/Position Reference
Additional Information
Statement Reference

Assay mode
Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Synonyms & Secondary IDs
Reported As
Symbol Synonym	(UAS)-PI3KDN (Cho et al., 2001) KD-Dp110 (Coelho et al., 2005) p110^DN (Duchek and Rorth, 2001) p110-D954A (Fulga and Rorth, 2002) P[UAS-Dp110^D954A] (Walker et al., 2006) P{Dp110^D954A} (FlyBase, 1996-) UAS-Dp110^D945A (Brumby and Richardson, 2003, Britton et al., 2002) UAS-dp110^D954A (Kramer et al., 2003) UAS-Dp110^D954A (Goberdhan et al., 1999, Mikeladze-Dvali et al., 2005) UASDp110^D954A (Wood et al., 2006) UAS-Dp110^DN (Reiling and Hafen, 2004) UAS-Dp110^KD (Coelho et al., 2005) UAS-Dp110-D954A (Teleman and Cohen, 2000) UAS-Dp110DN (Bruckner et al., 2004, Bruckner et al., 2004) UAS-dPI3K^DN (Wu et al., 2005) UAS-dPI3K-DN (Kramer et al., 2003) UAS-mycDp110^D954A (Betschinger et al., 2006) UAS-PI3K92E-Dp110^D945A (Herranz et al., 2006) UAS-PI3K^D954A (Raisin et al., 2003) UAS-Pi3K^DN (Colombani et al., 2005, Colombani et al., 2005) UAS-PI3K^DN (Colombani et al., 2003) UAS-PI3K DN (Yang, 2005) UAS-PI3KDN (Gao et al., 2000) UAS-PI3Kp110 DN (Yang et al., 2005)
Secondary FlyBase IDs

References ( 36 )

Generate a list of	All references relating to this transgenic transposon ( 36 )

List References by type	Research paper ( 32 ) Supplementary material ( 3 ) FlyBase analysis ( 1 )
Recent research papers ( 4 )
	Betschinger et al., 2006, Cell 124(6): 1241--1253 Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. [FBrf0189901] Herranz et al., 2006, Development 133(14): 2617--2625 calderon encodes an organic cation transporter of the major facilitator superfamily required for cell growth and proliferation of Drosophila tissues. [FBrf0194487] Walker et al., 2006, Genes Dev. 20(23): 3311--3323 Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons. [FBrf0193208] Wood et al., 2006, J. Cell Biol. 173(3): 405--416 Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster. [FBrf0190948] Show all research papers ...

Recombinant construct P{Dp110D954A}

Recombinant construct P{Dp110^D954A}