Recombinant construct P{UAS-Fra.Fbz}

General Information
Symbol	P{UAS-Fra.Fbz}	FlyBase ID	FBtp0007879
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	2 available
Molecular map
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Eresh et al., 1997)
Uses	CV term Qualifiers & info Reference binary system (targeted) kay (Eresh et al., 1997) characterization kay (Eresh et al., 1997)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Eresh et al., 1997)
Component Alleles
Allele	kay^Fbz.Scer\UAS
Reference(s)	(Eresh et al., 1997, Sanyal et al., 2002, Szuts and Bienz, 2000, Riese et al., 1997, Riesgo-Escovar and Hafen, 1997, Ciapponi et al., 2001, Collins et al., 2006, Rallis et al., 2010, Franciscovich et al., 2008, Lehmann et al., 2002, Xiong et al., 2010, Lee et al., 2010, Nechipurenko and Broihier, 2012, Freeman et al., 2010)
Molecular data	Construct: Amino acids 252-337 (the bZIP fragment) are cloned into the pUAST germline transformation vector. (Eresh et al., 1997)
Phenotypic class	neuroanatomy defective, with Scer\GAL4^elav-C155 (Sanyal et al., 2002, Franciscovich et al., 2008) neuroanatomy defective, with Scer\GAL4^ey-OK107 (Rallis et al., 2010) neuroanatomy defective \| conditional, with Scer\GAL4^tey-5053A (Xiong et al., 2010) neurophysiology defective, with Scer\GAL4^elav-C155 (Sanyal et al., 2002, Franciscovich et al., 2008) planar polarity defective, with Scer\GAL4^h-1J3 (Ciapponi et al., 2001) planar polarity defective, with Scer\GAL4^hs.2sev (Ciapponi et al., 2001) visible, with Scer\GAL4^ey.3.5.Exel (Franciscovich et al., 2008)
Phenotype manifest in	adult midgut precursor cell, with Scer\GAL4^48Y (Riese et al., 1997) anterior crossvein, with Scer\GAL4^dpp.blk1 (Ciapponi et al., 2001) anterior crossvein, with Scer\GAL4^en-e16E (Ciapponi et al., 2001) axon, with Scer\GAL4^ey-OK107 (Rallis et al., 2010) bouton, with Scer\GAL4^BG380 (Collins et al., 2006) bouton, with Scer\GAL4^elav-C155 (Sanyal et al., 2002) cuprophilic cell, with Scer\GAL4^48Y (Riese et al., 1997) cuprophilic cell, with Scer\GAL4^hs.PB (Riese et al., 1997) cuprophilic cell, with Scer\GAL4^unspecified (Eresh et al., 1997) eye, with Scer\GAL4^ey.3.5.Exel (Franciscovich et al., 2008) eye, with Scer\GAL4^h-1J3 (Ciapponi et al., 2001) eye, with Scer\GAL4^hs.2sev (Ciapponi et al., 2001) eye, with Scer\GAL4^unspecified (Eresh et al., 1997) eye photoreceptor cell, with Scer\GAL4^h-1J3 (Ciapponi et al., 2001) eye photoreceptor cell, with Scer\GAL4^hs.2sev (Ciapponi et al., 2001) Kenyon cell, with Scer\GAL4^ey-OK107 (Rallis et al., 2010) midgut interstitial cell, with Scer\GAL4^48Y (Riese et al., 1997) neuromuscular junction, with Scer\GAL4^BG380 (Collins et al., 2006) neuromuscular junction \| larval stage, with Scer\GAL4^elav-C155 (Sanyal et al., 2002) ommatidium, with Scer\GAL4^h-1J3 (Ciapponi et al., 2001) ommatidium, with Scer\GAL4^hs.2sev (Ciapponi et al., 2001) segmental nerve \| conditional, with Scer\GAL4^tey-5053A (Xiong et al., 2010) synapse, with Scer\GAL4^elav-C155 (Franciscovich et al., 2008) terminal bouton, with Scer\GAL4^elav-C155 (Franciscovich et al., 2008) wing vein, with Scer\GAL4^en-e16E (Ciapponi et al., 2001) wing vein, with Scer\GAL4^sd-SG29.1, kay¹ (Ciapponi et al., 2001) wing vein L2, with Scer\GAL4^sd-SG29.1 (Ciapponi et al., 2001) wing vein L3, with Scer\GAL4^dpp.blk1, kay¹ (Ciapponi et al., 2001) wing vein L4, with Scer\GAL4^sd-SG29.1 (Ciapponi et al., 2001) wing vein L5, with Scer\GAL4^en-e16E (Ciapponi et al., 2001) wing vein L5, with Scer\GAL4^en-e16E, kay¹ (Ciapponi et al., 2001) wing vein L5, with Scer\GAL4^sd-SG29.1 (Ciapponi et al., 2001)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 2 )
Bloomington	7214 w¹¹¹⁸; P{UAS-Fra.Fbz}5 7215 y¹ w¹¹¹⁸; P{UAS-Fra.Fbz}7
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	D-Fos^bZIP (Ciapponi et al., 2001) Fbz (Xiong et al., 2010) P{UAS-Fra.Fbz} (FlyBase, 1996-) UAS.Fbz (Szuts and Bienz, 2000) UAS-fbz (Sanyal et al., 2002) UAS-Fbz (Rallis et al., 2010, Franciscovich et al., 2008, Lehmann et al., 2002, Freeman et al., 2010) UAS-fos^DN (Nechipurenko and Broihier, 2012) UAS-Fos^DN (Xiong et al., 2010) UAS-Fos^DN (Fbz) (Collins et al., 2006) UAS-Fos-DN (Lee et al., 2010)
Secondary FlyBase IDs

References ( 14 )
Research paper	Nechipurenko and Broihier, 2012, J. Cell Biol. 196(3): 345--362 FoxO limits microtubule stability and is itself negatively regulated by microtubule disruption. [FBrf0217391] Freeman et al., 2010, Brain Res. 1326: 15--29 A new genetic model of activity-induced Ras signaling dependent pre-synaptic plasticity in Drosophila. [FBrf0210453] Lee et al., 2010, J. Neurosci. 30(50): 16959--16969 LRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsynaptic compartments of the Drosophila neuromuscular junction. [FBrf0212570] Rallis et al., 2010, Dev. Biol. 339(1): 65--77 Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability. [FBrf0209975] Xiong et al., 2010, J. Cell Biol. 191(1): 211--223 Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. [FBrf0211939] Franciscovich et al., 2008, Genetics 180(4): 2057--2071 Overexpression screen in Drosophila identifies neuronal roles of GSK-3 beta/shaggy as a regulator of AP-1-dependent developmental plasticity. [FBrf0207092] Collins et al., 2006, Neuron 51(1): 57--69 Highwire restrains synaptic growth by attenuating a MAP kinase signal. [FBrf0194919] Lehmann et al., 2002, Cell Death Differ. 9(5): 581--590 AP-1, but not NF-kappaB, is required for efficient steroid-triggered cell death in Drosophila. [FBrf0146921] Ciapponi et al., 2001, Genes Dev. 15(12): 1540--1553 Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites. [FBrf0136943] Szuts and Bienz, 2000, Mech. Dev. 98(1-2): 71--76 An autoregulatory function of Dfos during Drosophila endoderm induction. [FBrf0130104] Eresh et al., 1997, EMBO J. 16(8): 2014--2022 A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. [FBrf0093434] Riese et al., 1997, Development 124(17): 3353--3361 D-Fos, a target gene of Decapentaplegic signalling with a critical role during Drosophila endoderm induction. [FBrf0098335] Riesgo-Escovar and Hafen, 1997, Science 278(5338): 669--672 Common and distinct roles of DFos and DJun during Drosophila development. [FBrf0098878]
Letter	Sanyal et al., 2002, Nature 416(6883): 870--874 AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila. [FBrf0147170]