Recombinant construct P{UAS-dm.Z}

General Information
Symbol	P{UAS-dm.Z}	FlyBase ID	FBtp0010023
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	3 available
Molecular map
Recent Updates
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FB2013_03
FB2013_02	Controlled Vocabulary Terms embryonic/larval fat body heat sensitive
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Zaffran et al., 1998)
Uses	CV term Qualifiers & info Reference binary system (targeted) dm (Zaffran et al., 1998) characterization dm (Zaffran et al., 1998)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Zaffran et al., 1998) selectable marker (Zaffran et al., 1998)
Component Alleles
Allele	dm^Scer\UAS.cZa
Reference(s)	(Zaffran et al., 1998, Berry and Baehrecke, 2007, Perrin et al., 2003, Goodliffe et al., 2005, Jiao et al., 2001, Orian et al., 2003, Britton et al., 2002, Xue and Noll, 2002, Colombani et al., 2005, Hennig and Neufeld, 2002, Moberg et al., 2004, Prober and Edgar, 2002, Duman-Scheel et al., 2004, Pierce et al., 2004, Quinn et al., 2004, Prober and Edgar, 2000, de la Cova et al., 2004, Reis and Edgar, 2004, Frei et al., 2005, Shcherbata et al., 2004, Bateman and McNeill, 2004, Tapon et al., 2001, Pielage et al., 2003, Johnston et al., 1999, Parker, 2006, Betschinger et al., 2006, Nolo et al., 2006, Li and Baker, 2007, Secombe et al., 2007, Simcox et al., 2008, Mortimer and Moberg, 2007, Reddy and Irvine, 2011, Khan et al., 2009, Steiger et al., 2008, Montero et al., 2008, Steiger et al., 2008, Wang and Huang, 2009, Goodliffe et al., 2007, Ziosi et al., 2010, Neto-Silva et al., 2010, Furrer et al., 2010, Marinho et al., 2011, Mitchell et al., 2010, Li et al., 2010, Kawamori and Yamaguchi, 2011, Orian et al., 2007, Li et al., 2010, Becam et al., 2011, Unhavaithaya and Orr-Weaver, 2012, Xu et al., 2008, Datar et al., 2006, Benassayag et al., 2005, Herranz et al., 2010, Daneshvar et al., 2013, Wang et al., 2008)
Molecular data	Construct: Scer\UAS regulatory sequences drive expression of a dm cDNA. (Zaffran et al., 1998)
Phenotypic class	cell growth defective, with Scer\GAL4^Aug21 (Colombani et al., 2005) cell growth defective \| cell non-autonomous \| somatic clone, with Scer\GAL4^Act5C.PP (de la Cova et al., 2004) cell growth defective \| somatic clone, with Scer\GAL4^Act5C.PP (de la Cova et al., 2004) decreased cell number \| adult stage, with Scer\GAL4^en-e16E (Wang et al., 2008) endomitotic cell cycle defective, with Scer\GAL4^moody.PS (Unhavaithaya and Orr-Weaver, 2012) endomitotic cell cycle defective \| somatic clone \| third instar larval stage, with Scer\GAL4^Act5C.PP (Datar et al., 2006) increased cell death, with Scer\GAL4^ap-md544 (Montero et al., 2008, Benassayag et al., 2005) increased cell death, with Scer\GAL4^dpp.blk1 (de la Cova et al., 2004) increased cell death, with Scer\GAL4^GMR.PF (Montero et al., 2008) increased cell death, with Scer\GAL4^αTub84B.PC (de la Cova et al., 2004) increased cell death \| cell non-autonomous, with Scer\GAL4^dpp.blk1 (de la Cova et al., 2004) increased cell death \| cell non-autonomous \| somatic clone, with Scer\GAL4^Act5C.PP (de la Cova et al., 2004) increased cell death \| somatic clone, with Scer\GAL4^Act5C.PP (Benassayag et al., 2005) increased cell death \| somatic clone, with Scer\GAL4^hh.PU (Ziosi et al., 2010) increased cell number \| third instar larval stage, with Scer\GAL4^repo.PU (Reddy and Irvine, 2011) increased cell size, with Scer\GAL4^GMR.PF (Quinn et al., 2004, Secombe et al., 2007) increased cell size, with Scer\GAL4^ptc-559.1 (Marinho et al., 2011) increased cell size \| adult stage, with Scer\GAL4^en-e16E (Wang et al., 2008) increased cell size \| somatic clone, with Scer\GAL4^Act5C.PI (Marinho et al., 2011) increased cell size \| somatic clone, with Scer\GAL4^Act5C.PP (Prober and Edgar, 2002, Bateman and McNeill, 2004, Benassayag et al., 2005) increased cell size \| somatic clone, with Scer\GAL4^αTub84B.PL (Grewal et al., 2005) lethal, with Scer\GAL4^da.G32 (Daneshvar et al., 2013) lethal \| heat sensitive, with Scer\GAL4^dm-PG45 (Benassayag et al., 2005) lethal \| larval stage, with Scer\GAL4^da.G32 (Khan et al., 2009) mitotic cell cycle defective, with Scer\GAL4^Act5C.PP (Reis and Edgar, 2004) mitotic cell cycle defective \| somatic clone, with Scer\GAL4^Act5C.PP (Benassayag et al., 2005) size defective \| adult stage, with Scer\GAL4^GMR.PF (Xu et al., 2008) size defective \| somatic clone, with Scer\GAL4^Act5C.PI (Marinho et al., 2011) small body \| larval stage, with Scer\GAL4^da.G32 (Khan et al., 2009) visible, with Scer\GAL4^ap-md544 (Furrer et al., 2010) visible, with Scer\GAL4^GMR.PF (Secombe et al., 2007, Steiger et al., 2008, Montero et al., 2008, Furrer et al., 2010, Li et al., 2010) visible \| adult stage, with Scer\GAL4^GMR.PF (Xu et al., 2008)
Phenotype manifest in	cell, with Scer\GAL4^Act5C.PP (Johnston et al., 1999) cell, with Scer\GAL4^bbg-C96 (Johnston et al., 1999) cell, with Scer\GAL4^en-e16E (Johnston et al., 1999) cell cycle, with Scer\GAL4^Act5C.PP (Johnston et al., 1999) cell cycle, with Scer\GAL4^bbg-C96 (Johnston et al., 1999) dorsal-ventral compartment boundary of the wing \| third instar larval stage, with Scer\GAL4^sd-SG29.1 (Becam et al., 2011) embryonic/larval brain \| third instar larval stage, with Scer\GAL4^repo.PU (Reddy and Irvine, 2011) embryonic/larval fat body \| somatic clone \| third instar larval stage, with Scer\GAL4^Act5C.PP (Datar et al., 2006) embryonic/larval glial cell \| third instar larval stage, with Scer\GAL4^repo.PU (Reddy and Irvine, 2011) eye, with Scer\GAL4^GMR.PF (Quinn et al., 2004, Secombe et al., 2007, Steiger et al., 2008, Steiger et al., 2008, Montero et al., 2008, Li et al., 2010, Xu et al., 2008) eye disc, with Scer\GAL4^GMR.PF (Quinn et al., 2004, Montero et al., 2008) eye disc \| third instar larval stage, with Scer\GAL4^repo.PU (Reddy and Irvine, 2011) eye photoreceptor cell, with Scer\GAL4^GMR.PF (Secombe et al., 2007) follicle cell & nucleus \| somatic clone, with Scer\GAL4^Act5C.PP (Shcherbata et al., 2004) larval salivary gland & nucleolus, with Scer\GAL4^en-e16E (Grewal et al., 2005) mitotic cell cycle, with Scer\GAL4^Act5C.PP (Reis and Edgar, 2004) mitotic cell cycle \| somatic clone, with Scer\GAL4^Act5C.PP (Prober and Edgar, 2002) nucleolus, with Scer\GAL4^en-e16E (Grewal et al., 2005) nucleolus, with Scer\GAL4^ptc-559.1 (Grewal et al., 2005, Marinho et al., 2011) nucleolus, with Scer\GAL4^sca-109-68 (Kawamori and Yamaguchi, 2011) nucleus, with Scer\GAL4^ptc-559.1 (Grewal et al., 2005, Marinho et al., 2011) nucleus, with Scer\GAL4^sca-109-68 (Kawamori and Yamaguchi, 2011) ommatidium, with Scer\GAL4^GMR.PF (Quinn et al., 2004, Secombe et al., 2007, Steiger et al., 2008, Steiger et al., 2008, Montero et al., 2008, Furrer et al., 2010) pigment cell, with Scer\GAL4^GMR.PF (Steiger et al., 2008) posterior scutellar bristle, with Scer\GAL4^sca-109-68 (Kawamori and Yamaguchi, 2011) ring canal, with Scer\GAL4^Aug21 (Colombani et al., 2005) salivary gland \| somatic clone, with Scer\GAL4^Act5C.PP (Furrer et al., 2010) subperineurial glial cell, with Scer\GAL4^moody.PS (Unhavaithaya and Orr-Weaver, 2012) trichogen cell, with Scer\GAL4^sca-109-68 (Kawamori and Yamaguchi, 2011) ventral nerve cord primordium, with Scer\GAL4^rho.PU (Orian et al., 2007) wing, with Scer\GAL4^ap-md544 (Furrer et al., 2010) wing, with Scer\GAL4^αTub84B.PC (de la Cova et al., 2004) wing \| posterior, with Scer\GAL4^en-e16E (Wang et al., 2008) wing disc, with Scer\GAL4^ap-md544 (Montero et al., 2008, Benassayag et al., 2005) wing disc \| somatic clone, with Scer\GAL4^Act5C.PP (Furrer et al., 2010, Benassayag et al., 2005)
Other information

Allele	w^+mC
Reference(s)	(Zaffran et al., 1998)
Molecular data	Minigene of the white cDNA. (Chung et al., 1993) 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors.
Phenotypic class	courtship behavior defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 2 )
Bloomington	9674 w¹¹¹⁸; P{UAS-dm.Z}132 9675 P{hsFLP}22, y¹ w^*; P{UAS-dm.Z}42
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{UAS-dm.Z} (FlyBase, 1996-) UAS>dmyc (Unhavaithaya and Orr-Weaver, 2012) UAS-dm (Quinn et al., 2004) UAS-dMyc (Colombani et al., 2005, Frei et al., 2005, Shcherbata et al., 2004, Moberg et al., 2004, Pierce et al., 2004, de la Cova et al., 2004, Orian et al., 2003, Hennig and Neufeld, 2002, Prober and Edgar, 2002, Britton et al., 2002, Prober and Edgar, 2000, Montero et al., 2008, Betschinger et al., 2006, Secombe et al., 2007, Becam et al., 2011, Wang and Huang, 2009, Marinho et al., 2011, Li et al., 2010, Kawamori and Yamaguchi, 2011, Orian et al., 2007, Datar et al., 2006, Benassayag et al., 2005, Herranz et al., 2010, Mortimer and Moberg, 2007) UAS-dmyc (Goodliffe et al., 2005, Reis and Edgar, 2004, Pielage et al., 2003, Tapon et al., 2001, Goodliffe et al., 2007, Daneshvar et al., 2013, Neto-Silva et al., 2010) UASdmyc (Perrin et al., 2003, Khan et al., 2009, Ziosi et al., 2010) UAS-D-Myc (Jiao et al., 2001) UAS-dmyc⁴² (Duman-Scheel et al., 2004) UAS-dMyc⁴² (Johnston et al., 1999) UASMyc (Bateman and McNeill, 2004) UAS-Myc (Xue and Noll, 2002, Steiger et al., 2008, Nolo et al., 2006, Berry and Baehrecke, 2007, Simcox et al., 2008, Steiger et al., 2008, Li et al., 2010, Wang et al., 2008, Reddy and Irvine, 2011) UAS-myc (Li and Baker, 2007, Mitchell et al., 2010, Xu et al., 2008)
Secondary FlyBase IDs

References ( 55 )

Generate a list of	All references relating to this transgenic transposon ( 55 )

List References by type	Research paper ( 53 ) Supplementary material ( 2 )
Recent research papers ( 6 )
	Daneshvar et al., 2013, Biol. Open 2(1): 1--9 MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila. [FBrf0220584] Unhavaithaya and Orr-Weaver, 2012, Genes Dev. 26(1): 31--36 Polyploidization of glia in neural development links tissue growth to blood-brain barrier integrity. [FBrf0217041] Becam et al., 2011, Development 138(17): 3781--3789 Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing. [FBrf0214603] Kawamori and Yamaguchi, 2011, Cell Struct. Funct. 36(1): 103--119 DREF is Critical for Drosophila Bristle Development by Regulating Endoreplication in Shaft Cells. [FBrf0213809] Marinho et al., 2011, Development 138(2): 349--357 The Drosophila Nol12 homologue viriato is a dMyc target that regulates nucleolar architecture and is required for dMyc-stimulated cell growth. [FBrf0212565] Reddy and Irvine, 2011, Development 138(23): 5201--5212 Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling. [FBrf0216584] Show all research papers ...