Recombinant construct P{UAS-RasGAP.Myc}

General Information
Symbol	P{UAS-RasGAP.Myc}	FlyBase ID	FBtp0010847
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	0 available
Molecular map
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Feldmann et al., 1999)
Uses	CV term Qualifiers & info Reference binary system (targeted) RasGAP (Feldmann et al., 1999) characterization RasGAP (Feldmann et al., 1999)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Feldmann et al., 1999) molecular tag (Feldmann et al., 1999) selectable marker (Feldmann et al., 1999)
Component Alleles
Allele	vap^{Scer\UAS.T:Hsap\MYC}
Reference(s)	(Feldmann et al., 1999, Botella et al., 2003, Walker et al., 2006, Woodcock and Hughes, 2004)
Molecular data	Construct: A full length vap cDNA tagged with vap is expressed under the control of Scer\UAS regulatory sequences. (Feldmann et al., 1999)
Phenotypic class	visible, with Scer\GAL4^Bx-MS1096 (Feldmann et al., 1999)
Phenotype manifest in	wing, with Scer\GAL4^Bx-MS1096 (Feldmann et al., 1999)
Other information

Allele	w^+mC
Reference(s)	(Feldmann et al., 1999)
Molecular data	Minigene of the white cDNA. (Chung et al., 1993) 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors.
Phenotypic class	courtship behavior defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	P[UAS-RasGAP] (Botella et al., 2003, Walker et al., 2006) P{UAS-RasGAP.Myc} (FlyBase, 1996-)
Secondary FlyBase IDs

References ( 4 )
Research paper	Walker et al., 2006, Genes Dev. 20(23): 3311--3323 Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons. [FBrf0193208] Woodcock and Hughes, 2004, Biochem. J. 380(3): 767--774 p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila. [FBrf0179968] Botella et al., 2003, Mol. Biol. Cell 14(1): 241--250 Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap. [FBrf0155942] Feldmann et al., 1999, Mol. Cell. Biol. 19(3): 1928--1937 Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 ras-GTPase-activating protein. [FBrf0106478]