Recombinant construct P{UAS-DnaJ-1.K}

General Information
Symbol	P{UAS-DnaJ-1.K}	FlyBase ID	FBtp0012543
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	1 available
Molecular map
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Kazemi-Esfarjani and Benzer, 2000)
Uses	CV term Qualifiers & info Reference binary system (targeted) DnaJ-1 (Kazemi-Esfarjani and Benzer, 2000) characterization DnaJ-1 (Kazemi-Esfarjani and Benzer, 2000)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Kazemi-Esfarjani and Benzer, 2000)
Component Alleles
Allele	DnaJ-1^Scer\UAS.cKa
Reference(s)	(Kazemi-Esfarjani and Benzer, 2000, Takeyama et al., 2002, Tsai et al., 2004, Chartier et al., 2006, Wang et al., 2012, Fayazi et al., 2006, Ghosh and Feany, 2004, Nisoli et al., 2010, Doumanis et al., 2009, Nishimura et al., 2010)
Molecular data	Construct: Scer\UAS regulatory sequences drive expression of DnaJ-1 coding sequences. (Kazemi-Esfarjani and Benzer, 2000)
Phenotypic class
Phenotype manifest in
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 1 )
Bloomington	30553 w^*; P{UAS-DnaJ-1.K}3
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{UAS-dHdj1} (Tsai et al., 2004) P{UAS-DnaJ-1.K} (FlyBase, 1996-) UAS-dhdj-1 (Takeyama et al., 2002) UAS-dhdJ1 (Kazemi-Esfarjani and Benzer, 2000, Chartier et al., 2006, Doumanis et al., 2009, Fayazi et al., 2006) UAS-dhdj1 (Wang et al., 2012) UAS-dHdj1 (Nisoli et al., 2010) UAS-dHDJ1 (Nishimura et al., 2010) UAS-DNAJ1 (Ghosh and Feany, 2004)
Secondary FlyBase IDs

References ( 11 )
Research paper	Wang et al., 2012, Aging Cell 11(1): 93--103 Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in Drosophila. [FBrf0217184] Nishimura et al., 2010, J. Neurogenet. 24(4): 194--206 Selection of Behaviors and Segmental Coordination During Larval Locomotion Is Disrupted by Nuclear Polyglutamine Inclusions in a New Drosophila Huntington's Disease-Like Model. [FBrf0212327] Nisoli et al., 2010, Cell Death Differ. 17(10): 1577--1587 Neurodegeneration by polyglutamine Atrophin is not rescued by induction of autophagy. [FBrf0212035] Doumanis et al., 2009, PLoS ONE 4(9): e7275 RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation. [FBrf0209128] Chartier et al., 2006, EMBO J. 25(10): 2253--2262 A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1. [FBrf0190356] Fayazi et al., 2006, Neurobiol. Disease 24(2): 226--244 A Drosophila ortholog of the human MRJ modulates polyglutamine toxicity and aggregation. [FBrf0193414] Ghosh and Feany, 2004, Hum. Mol. Genet. 13(18): 2011--2018 Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. [FBrf0180337] Tsai et al., 2004, Proc. Natl. Acad. Sci. U.S.A. 101(12): 4047--4052 Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors. [FBrf0175091] Takeyama et al., 2002, Neuron 35(5): 855--864 Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila. [FBrf0152267] Kazemi-Esfarjani and Benzer, 2000, Science 287(5459): 1837--1840 Genetic suppression of polyglutamine toxicity in Drosophila. [FBrf0126796]
Personal communication to FlyBase	Kazemi-Esfarjani, 2010.5.11, UAS-DnaJ-1.K insertion from Parsa Kazemi-Esfarjani. UAS-DnaJ-1.K insertion from Parsa Kazemi-Esfarjani. [FBrf0210715]