Recombinant construct P{GMR-Nc.H}

General Information
Symbol	P{GMR-Nc.H}	FlyBase ID	FBtp0013380
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	0 available
Molecular map
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Hawkins et al., 2000)
Uses	CV term Qualifiers & info Reference characterization Nc (Hawkins et al., 2000) GMR construct Nc (Hawkins et al., 2000)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference ectopic expression (Hawkins et al., 2000) selectable marker (Hawkins et al., 2000)
Component Alleles
Allele	Nc^GMR.PH
Reference(s)	(Hawkins et al., 2000, Yu et al., 2002, Copeland et al., 2007, Xu et al., 2003, Muro et al., 2006, Huh et al., 2007, Hsu et al., 2004, Verghese et al., 2012)
Molecular data	Construct: GMR regulatory sequences drive expression of full length wild-type Nc. (Hawkins et al., 2000)
Phenotypic class	eye color defective (Hawkins et al., 2000) visible (Hawkins et al., 2000, Huh et al., 2007, Copeland et al., 2007)
Phenotype manifest in	eye (Hawkins et al., 2000, Huh et al., 2007, Copeland et al., 2007) eye photoreceptor cell (Hawkins et al., 2000) pigment cell (Hawkins et al., 2000) retina (Hawkins et al., 2000, Muro et al., 2006)
Other information

Allele	w^+mC
Reference(s)	(Hawkins et al., 2000)
Molecular data	Minigene of the white cDNA. (Chung et al., 1993) 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors.
Phenotypic class	courtship behavior defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	GMR-Dronc (Xu et al., 2003, Huh et al., 2007, Copeland et al., 2007, Verghese et al., 2012) GMRDronc (Yu et al., 2002) GMR-DRONC (Hawkins et al., 2000) GMR-Nc (Muro et al., 2006) P[GMRhid] (Hsu et al., 2004) P{GMR-Nc.H} (FlyBase, 1996-)
Secondary FlyBase IDs

References ( 8 )
Research paper	Verghese et al., 2012, Cell Death Differ. 19(10): 1664--1676 Hippo signalling controls Dronc activity to regulate organ size in Drosophila. [FBrf0219371] Copeland et al., 2007, BMC Dev. Biol. 7: 82 echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases. [FBrf0200872] Huh et al., 2007, J. Biol. Chem. 282(3): 2056--2068 The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers. [FBrf0192423] Muro et al., 2006, Development 133(17): 3305--3315 The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. [FBrf0192459] Hsu et al., 2004, J. Neurosci. 24(2): 500--507 Limited role of developmental programmed cell death pathways in Drosophila norpA retinal degeneration. [FBrf0167807] Xu et al., 2003, Curr. Biol. 13(9): 790--795 The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. [FBrf0158821] Yu et al., 2002, Development 129(13): 3269--3278 A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye. [FBrf0148973] Hawkins et al., 2000, J. Biol. Chem. 275(35): 27084--27093 The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM. [FBrf0129853]