Recombinant construct P{ato-tau-myc}

General Information
Symbol	P{ato-tau-myc}	FlyBase ID	FBtp0022601
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	0 available
Molecular map
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Bazigou et al., 2007, Senti et al., 2003)
Uses	CV term Qualifiers & info Reference characterization ato (Bazigou et al., 2007)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference molecular tag (Bazigou et al., 2007) selectable marker (Senti et al., 2003)
Component Alleles
Allele	Btau\MAPT^{ato.hs.T:Hsap\MYC}
Reference(s)	(Bazigou et al., 2007, Senti et al., 2003, Senti et al., 2003, Tomasi et al., 2008, Sato et al., 2006, Timofeev et al., 2012, Petrovic and Hummel, 2008)
Molecular data	Two copies of a 2kb SalI-XbaI R8-specific enhancer fragment from the ato gene is fused upstream of a minimal Hsp70 promoter driving expression of bovine Btau\MAPT tagged with six copies of T:Hsap\MYC. (Senti et al., 2003)
Phenotypic class
Phenotype manifest in
Other information

Allele	w^+mC
Reference(s)	(Senti et al., 2003)
Molecular data	Minigene of the white cDNA. (Chung et al., 1993) 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors.
Phenotypic class	courtship behavior defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference adult stage photoreceptor cell R8 (Tomasi et al., 2008) distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference pupal stage P6 -- P7 medulla anlage \| distal & restricted (Timofeev et al., 2012) Comment:24-42h APF pupal stage P6 -- pharate adult stage P8 photoreceptor cell R8 • axon (Timofeev et al., 2012) Comment:24-55h APF pharate adult stage P8 medulla layer M3 (Timofeev et al., 2012) Comment:55h APF
Additional Information
Statement Reference Btau\MAPT[ato.hs.T:Hsap\MYC] drives expression early in axons of photoreceptor R8. (Timofeev et al., 2012)

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	ato-tau-myc (Timofeev et al., 2012) ato-τ-myc (Bazigou et al., 2007) ato-τmyc (Senti et al., 2003, Senti et al., 2003, Tomasi et al., 2008, Sato et al., 2006, Petrovic and Hummel, 2008) P{ato-tau-myc} (FlyBase, 1992-)
Secondary FlyBase IDs

References ( 7 )
Research paper	Timofeev et al., 2012, Neuron 75(1): 80--93 Localized netrins act as positional cues to control layer-specific targeting of photoreceptor axons in Drosophila. [FBrf0218874] Petrovic and Hummel, 2008, Nature 456(7223): 800--803 Temporal identity in axonal target layer recognition. [FBrf0206960] Tomasi et al., 2008, Neuron 57(5): 691--704 The transmembrane protein Golden goal regulates R8 photoreceptor axon-axon and axon-target interactions. [FBrf0204453] Bazigou et al., 2007, Cell 128(5): 961--975 Anterograde jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila. [FBrf0192674] Sato et al., 2006, Nat. Neurosci. 9(1): 67--75 DWnt4 regulates the dorsoventral specificity of retinal projections in the Drosophila melanogaster visual system. [FBrf0191282] Senti et al., 2003, Curr. Biol. 13(10): 828--832 Flamingo regulates R8 axon-axon and axon-target interactions in the Drosophila visual system. [FBrf0158822]
Supplementary material	Senti et al., 2003, Curr. Biol. 13(10): Supplemental Data. [FBrf0210353]