FB2025_01 , released February 20, 2025
Recombinant Construct: P{Sym-UAS-Ilp3}
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General Information
Symbol
P{Sym-UAS-Ilp3}
FlyBase ID
FBtp0051834
Feature type
transgenic_transposable_element
Component Allele(s)
Ilp3RNAi.Sym.UAS
Size
Expression Data
Associated insertion(s)
0 available
Molecular map
Description and Uses
Construct components
Component allele Ilp3RNAi.Sym.UAS
Transgenic product class
RNAi_reagent
(Buch et al., 2008)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ilp3
Description

Sense-antisense transcription of a 370bp fragment of Ilp3 cDNA (driven by two convergent arrays of UAS regulatory sequences) results in double stranded RNA (dsRNA) expression.

(Buch et al., 2008)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments

Likely due to sequence homology amongst the insulin-like peptides, the P{Sym-UAS-Ilp3} construct show off-target effects; as well as downregulating the levels of Ilp3 expression, it also downregulates the expression of Ilp2 and Ilp5.

(Buch et al., 2008)
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{Sym-UAS-Ilp3}
(FlyBase, 1996-)
UAS-dilp3 RNAi
(Buch et al., 2008)
d3Ri
(Buch et al., 2008)
Secondary FlyBase IDs
    References (2)