FB2025_01 , released February 20, 2025
Recombinant Construct: P{GAL4-dSREBPg.K}
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General Information
Symbol
P{GAL4-dSREBPg.K}
FlyBase ID
FBtp0051857
Feature type
transgenic_transposable_element
Component Allele(s)
SREBPGAL4::VP16
Also Known As
SREBP-Gal4, P{GAL4-dSREBPg}, Gal4-SREBP
Size
Expression Data
Associated insertion(s)
3 available
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
w+mC
Component allele SREBPGAL4::VP16
Transgenic product class
Component
Use(s)
Regulatory region(s)
SREBP
Encoded product / tool
SREBP
Tagged with
GAL4::VP16
Description

bHLH domain of SREBP has been replaced by sequence encoding a GAL4::VP16 driver in the context of a genomic fragment that is expressed under the control of the native SREBP promoter. The protein produced is subject to the same physiologically-regulated proteolytic processing as wild-type SREBP. Thus, this construct acts as a reporter to follow SREBP protein cleavage in vivo.

(Kunte et al., 2006)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (3)
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (11)
Reported As
Symbol Synonym
GAL4-SREBP
(Sieber and Spradling, 2015)
Gal4-SREBP
(Tsai et al., 2019, Wang et al., 2012)
Gal4-VP16-SREBP
(Tsai et al., 2019)
Gal4::SREBP
(Charroux and Royet, 2022)
P{GAL4-dSREBPg.K}
(FlyBase, 1992-)
P{GAL4-dSREBPg}
(Diop et al., 2015, Wang et al., 2012, Matthews et al., 2010)
P{GAL4-dSREPg}
(Matthews et al., 2009)
SREBP-GAL4
(Marianes and Spradling, 2013)
SREBP-Gal4
(Liu et al., 2024, Zhang et al., 2017, Reiff et al., 2015)
m-SREBP sensor
(Diop et al., 2015)
pP{GAL4-dSREBPg}
(Kunte et al., 2006)
Secondary FlyBase IDs
    References (16)