FB2025_01 , released February 20, 2025
Recombinant Construct: P{GMR58E02-GAL4}
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General Information
Symbol
P{GMR58E02-GAL4}
FlyBase ID
FBtp0061564
Feature type
transgenic_transposable_element
Component Allele(s)
Scer\GAL4GMR58E02
Also Known As
R58E02-GAL4, R58E02, GMR58E02-GAL4, 58E02-GAL4, PAM-Gal4, R58E02GAL4
Size
Expression Data
GAL4 reporter/driver
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
w+mC
Component allele Scer\GAL4GMR58E02
Transgenic product class
Component
Use(s)
Regulatory region(s)
GMR58E02
Encoded product / tool
GAL4
Description

A 1235 base pair fragment from the flanking non-coding or intronic region of DAT is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage
larval mushroom body dopaminergic neuron h1
(Saumweber et al., 2018, Rohwedder et al., 2016)
larval mushroom body dopaminergic neuron i1
(Saumweber et al., 2018, Rohwedder et al., 2016)
larval mushroom body dopaminergic neuron j1
(Saumweber et al., 2018, Rohwedder et al., 2016)
larval mushroom body dopaminergic neuron k1
(Rohwedder et al., 2016)
adult stage
mushroom body medial lobe | restricted
(Riemensperger et al., 2013)
adult dopaminergic PAM neuron
(Yamagata et al., 2015, Vogt et al., 2014, Perisse et al., 2013, Riemensperger et al., 2013, Liu et al., 2012)
adult brain | restricted
(Shuai et al., 2015, Yamagata et al., 2015)
mushroom body extrinsic neuron
(Shuai et al., 2015)
mushroom body gamma lobe slice 1
(Shuai et al., 2015)
mushroom body gamma lobe slice 2
(Shuai et al., 2015)
mushroom body gamma lobe slice 3
(Shuai et al., 2015)
mushroom body gamma lobe slice 4
(Shuai et al., 2015)
mushroom body gamma lobe slice 5
(Shuai et al., 2015)
mushroom body beta lobe slice 1
(Shuai et al., 2015)
mushroom body beta lobe slice 2
(Shuai et al., 2015)
mushroom body beta' lobe slice 1
(Shuai et al., 2015)
mushroom body beta' lobe slice 2
(Shuai et al., 2015)
mushroom body alpha lobe slice 1
(Shuai et al., 2015)
dopaminergic PAM neuron 13
(Shuai et al., 2015)
dopaminergic PAM neuron 14
(Shuai et al., 2015)
adult optic lobe glial cell
(Liu et al., 2012)
adult dopaminergic PAM neuron | subset
(Otto et al., 2020, Meissner et al., 2019, Huetteroth et al., 2015)
medial lobe of adult mushroom body
(Huetteroth et al., 2015)
Additional Information
Statement
Reference

Drives expression in a subset of dopaminergic protocerebral anterior medial (PAM) neurons.

(FlyBase Curators, 2017)

ScerGAL4GMR58E02 drives expression in ple positive larval dopaminergic pPAM neurons. Expression in larval dopaminergic pPAM2 neuron is stochastic and very rare.

(Rohwedder et al., 2016)

ScerGAL4GMR58E02 drives expression in mushroom body extrinsic neurons that innervate mushroom body gamma lobe slices 1, 2, 3, 4 and 5, mushroom body beta lobe slices 1 and 2, mushroom body beta' lobe slices 1 and 2 and mushroom body alpha lobe slice 1. Expression partially overlaps with that driven by EcollexAGMR24E12 in 13 dopaminergic PAM neurons 13 and 14.

(Shuai et al., 2015)

ScerGAL4GMR58E02 labels ~90 dopaminergic PAM neurons that innervate the medial lobe of the adult mushroom body.

(Huetteroth et al., 2015)

ScerGAL4GMR58E02 expression found in around 80% of dopaminergic PAM neurons. Labeled neurons project to mushroom body medial lobe.

(Riemensperger et al., 2013)

ScerGAL4GMR58E02 labels dopaminergic PAM neurons that innervate the alpha/beta surface Kenyon cells and alpha/beta core Kenyon cells.

(Perisse et al., 2013)

ScerGAL4GMR58E02 drives expression in DAT positive dopaminergic PAM neurons as well as adult optic lobe glial cells.

(Liu et al., 2012)
 
Marker for
adult dopaminergic PAM neuron
(Otto et al., 2020, Vogt et al., 2014)
Reflects expression of
DAT
(Liu et al., 2012)
Reporter construct used in assay
Progenitors and Descendants
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
41347
w1118; P{GMR58E02-GAL4}attP2
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (13)
Reported As
Symbol Synonym
58E02-GAL4
(Sareen et al., 2021)
58E02-Gal4
(Rajagopalan et al., 2023, Driscoll et al., 2021, Lesar et al., 2021)
GMR58E02-GAL4
(Aimon et al., 2023, Eichler et al., 2017)
GMR58E02-Gal4
(Kaldun et al., 2021, Widmer et al., 2018)
PAM-DAN-Gal4
(Bornstein et al., 2021)
PAM-Gal4
(Erhardt et al., 2023, Titos et al., 2023, Kaldun et al., 2021)
P{GMR58E02-GAL4}
(FlyBase, 1996-)
R58E02
(Erhardt et al., 2023, Wang et al., 2023, Chouhan and Sehgal, 2022, Marescotti et al., 2018, Saumweber et al., 2018, Robie et al., 2017, Rohwedder et al., 2016, Shuai et al., 2015, Perisse et al., 2013, FlyBase, 1996-)
R58E02-GAL4
(Jelen et al., 2023, Shen et al., 2023, Yamazaki et al., 2023, Hermanns et al., 2022, Miozzo et al., 2022, Mohandasan et al., 2022, Villar et al., 2022, Yamagata et al., 2022, French et al., 2021, Jacob et al., 2021, Kanno et al., 2021, Yamagata et al., 2021, Mishra et al., 2020, Otto et al., 2020, Scaplen et al., 2020, Corfas et al., 2019, Meissner et al., 2019, Senapati et al., 2019, Stern et al., 2019, Felsenberg et al., 2018, Ruppert et al., 2017, Sethi and Wang, 2017, Aso and Rubin, 2016, Yamagata et al., 2016, Huetteroth et al., 2015, Yamagata et al., 2015, Boto et al., 2014, Bou Dib et al., 2014, Lin et al., 2014, Vogt et al., 2014, Liu et al., 2012)
R58E02-Gal4
(Çoban et al., 2024, Ikeda et al., 2024, Mohammad et al., 2024, Petitgas et al., 2024, Sun et al., 2024, Gowda et al., 2023, Wu et al., 2023, Yang et al., 2023, Deere and Devineni, 2022, Lin et al., 2022, Bornstein et al., 2021, Jia et al., 2021, Landayan et al., 2021, Pütz et al., 2021, Weiss and Donlea, 2021, Zhao et al., 2021, Jacob and Waddell, 2020, Imai et al., 2019, Lyutova et al., 2019, Sun et al., 2018, Tas et al., 2018, Song et al., 2017, Cohn et al., 2015, Pech et al., 2013, Riemensperger et al., 2013)
R58E02-gal4
(Noyes and Davis, 2023)
R58E02GAL4
(Agrawal and Hasan, 2015)
R58E02Gal4
(Sun et al., 2024)
Secondary FlyBase IDs
    References (81)