FB2025_01 , released February 20, 2025
Recombinant Construct: P{UAS-2xAβ}
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General Information
Symbol
P{UAS-2xAβ}
FlyBase ID
FBtp0085679
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\APP2xAPP.SP.UAS
Also Known As
UAS-Aβ42, UAS-Aβ422X, UAS-Aβ42(2x), UAS-Aβ42(Human)
Size
Expression Data
Associated insertion(s)
0 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\APP2xAPP.SP.UAS
Transgenic product class
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\APP
Description

UAS regulatory sequences and a hsp70 minimal promoter drive expression of two copies of a 161 nucleotide fragment of Hsap\APP containing the Aβ sequence (corresponding to 1-42 amino acid residues. To ensure this fragment is secreted, a 232 nucleotide fragment containing the signal peptide from the aos gene.

(Casas-Tinto et al., 2011)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (16)
References (27)