FB2025_05 , released December 11, 2025
Recombinant Construct: P{UAS-hPRNP.V129.N159D.D167S.N174S}
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General Information
Symbol
P{UAS-hPRNP.V129.N159D.D167S.N174S}
FlyBase ID
FBtp0150881
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\PRNPV129.N159D.D167S.N174S.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\PRNPV129.N159D.D167S.N174S.UAS
Transgenic product class
missense_variant
(Myers et al., 2022)
polymorphic_sequence_variant
(Myers et al., 2022)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\PRNP
Description

UAS regulates expression of Hsap\PRNP, codon-optimized for Drosophila. The coding sequence carries the V129 polymorphism and also contains the N159D, D167S and N174S amino acid replacements.

(Myers et al., 2022)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hPRNP.V129.N159D.D167S.N174S}
(FlyBase, 1992-)
UAS-human PrP-N159D-D167S-N174S
(Myers et al., 2022)
Secondary FlyBase IDs
    References (3)