Evolutionary signatures for protein-coding genes

By studying evolution, we found this:



Revisiting the D. melanogaster protein-coding gene catalog

Purpose here is not to study gene evolution (see Eisen paper), but rather to leverage the 12 genomes to improve gene annotation quality.

 


Discovery of non-canonical genic phenomena

Conserved non-coding regions


Gene regulation


Discussion:  Assessing power to identify functional elements with 12 genomes