To return to FlyBase, see FlyBase Gene Report: Dmel\BRWD3.
The gene BRWD3 is referred to in FlyBase by the symbol Dmel\BRWD3 (CG31132, FBgn0011785). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: mitotic cell cycle G2/M transition DNA damage checkpoint; positive regulation of JAK-STAT cascade; phagocytosis, engulfment. 18 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Bromodomain; Bromodomain, conserved site; Quinonprotein alcohol dehydrogenase-like-superfamily; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval hindgut, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640098_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of BRWD3. Gene sequence location is 3R:20144722..20154341.