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This gene article is a stub. It has been seeded with the automatically generated summary from FlyBase release FB2013_02. Please help improve this summary by logging in and editing it.

To return to FlyBase, see FlyBase Gene Report: Dmel\CG18749.

Symbol Dmel\CG18749
Species Drosophila melanogaster
Annotation symbol CG18749
FlyBase ID FBgn0042182

This gene is referred to in FlyBase by the symbol Dmel\CG18749 (FBgn0042182). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: procollagen-proline 4-dioxygenase activity. Based on sequence similarity, it is predicted to be involved in the biological process: peptidyl-proline hydroxylation to 4-hydroxy-L-proline. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Oxoglutarate/iron-dependent dioxygenase; Prolyl 4-hydroxylase alpha-subunit, N-terminal; Prolyl 4-hydroxylase, alpha subunit. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1636894_s_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG18749 expression signal. See the GBrowse view of CG18749 to determine the overlapping gene(s). Gene sequence location is 3R:4069777..4073577.


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