To return to FlyBase, see FlyBase Gene Report: Dmel\CHKov1.
The gene CHKov1 is referred to in FlyBase by the symbol Dmel\CHKov1 (CG10618, FBgn0045761). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: RNA binding; RNA-directed DNA polymerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: RNA-dependent DNA replication. 6 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; tormogen cell. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: CHK kinase-like; Endonuclease/exonuclease/phosphatase; Protein kinase-like domain; Protein of unknown function DUF227; Reverse transcriptase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1624272_at partially aligns to an exonic region common to each of the 5 FlyBase-annotated transcript isoforms of CHKov1: 12 out of 13 probes fall into this exonic region. Gene sequence location is 3R:21148876..21155024.