To return to FlyBase, see FlyBase Gene Report: Dmel\GABA-B-R1.
|Name||metabotropic GABA-B receptor subtype 1|
The gene metabotropic GABA-B receptor subtype 1 is referred to in FlyBase by the symbol Dmel\GABA-B-R1 (CG15274, FBgn0260446). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: G-protein coupled GABA receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process: G-protein coupled receptor signaling pathway. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Extracellular ligand-binding receptor; GPCR, family 3, C-terminal; GPCR, family 3, gamma-aminobutyric acid receptor, type B; GPCR, family 3, gamma-aminobutyric acid receptor, type B1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1630047_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of GABA-B-R1. Gene sequence location is 2L:15017154..15034704.