To return to FlyBase, see FlyBase Gene Report: Dmel\Hop.
|Name||Hsp70/Hsp90 organizing protein homolog|
The gene Hsp70/Hsp90 organizing protein homolog is referred to in FlyBase by the symbol Dmel\Hop (CG2720, FBgn0024352). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: unfolded protein binding. Based on sequence similarity, it is predicted to be involved in the biological process: protein folding. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Heat shock chaperonin-binding; Tetratricopeptide TPR-1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, adult midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval midgut, adult hindgut, adult salivary gland, virgin spermatheca, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1630076_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Hop. Gene sequence location is 2L:295122..297449.