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This gene article is a stub. It has been seeded with the automatically generated summary from FlyBase release FB2013_02. Please help improve this summary by logging in and editing it.

To return to FlyBase, see FlyBase Gene Report: Dmel\Hph.

Symbol Dmel\Hph
Name HIF prolyl hydroxylase
Species Drosophila melanogaster
Annotation symbol CG44015
FlyBase ID FBgn0264785

The gene HIF prolyl hydroxylase is referred to in FlyBase by the symbol Dmel\Hph (CG44015, FBgn0264785). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: peptidyl-proline 4-dioxygenase activity; iron ion binding. There is experimental evidence that it is involved in the biological process: response to hypoxia; positive regulation of cell growth; protein localization; trachea morphogenesis; response to DNA damage stimulus; cellular response to hypoxia; terminal branching, open tracheal system. 43 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/larval tracheal system; terminal tracheal cell. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Oxoglutarate/iron-dependent dioxygenase; Prolyl 4-hydroxylase, alpha subunit; Zinc finger, MYND-type. Gene sequence location is 3R:1082759..1095232.


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