To return to FlyBase, see FlyBase Gene Report: Dmel\Hph.
|Name||HIF prolyl hydroxylase|
The gene HIF prolyl hydroxylase is referred to in FlyBase by the symbol Dmel\Hph (CG44015, FBgn0264785). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: peptidyl-proline 4-dioxygenase activity; iron ion binding. There is experimental evidence that it is involved in the biological process: response to hypoxia; positive regulation of cell growth; protein localization; trachea morphogenesis; response to DNA damage stimulus; cellular response to hypoxia; terminal branching, open tracheal system. 43 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/larval tracheal system; terminal tracheal cell. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Oxoglutarate/iron-dependent dioxygenase; Prolyl 4-hydroxylase, alpha subunit; Zinc finger, MYND-type. Gene sequence location is 3R:1082759..1095232.