To return to FlyBase, see FlyBase Gene Report: Dmel\PGRP-LB.
|Name||Peptidoglycan recognition protein LB|
The gene Peptidoglycan recognition protein LB is referred to in FlyBase by the symbol Dmel\PGRP-LB (CG14704, FBgn0037906). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; N-acetylmuramoyl-L-alanine amidase activity. There is experimental evidence that it is involved in the biological process: defense response to Gram-positive bacterium; negative regulation of peptidoglycan recognition protein signaling pathway. 8 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria; Peptidoglycan recognition protein, PGRP-S. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, larval/adult hindgut, adult heart, larval/adult salivary gland. Comments on Affy2 ProbeSet: ProbeSet 1630741_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of PGRP-LB. Gene sequence location is 3R:7278571..7286274.