To return to FlyBase, see FlyBase Gene Report: Dmel\Pkg21D.
|Name||cGMP-dependent protein kinase 21D|
The gene cGMP-dependent protein kinase 21D is referred to in FlyBase by the symbol Dmel\Pkg21D (CG3324, FBgn0000442). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cGMP-dependent protein kinase activity. There is experimental evidence that it is involved in the biological process: protein phosphorylation. 8 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: AGC-kinase, C-terminal; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; RmlC-like jelly roll fold; Serine/threonine- / dual specificity protein kinase, catalytic domain; Serine/threonine-protein kinase, active site; cGMP-dependent kinase; cGMP-dependent protein kinase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult hindgut, larval/adult Malpighian tubules. Comments on Affy2 ProbeSet: ProbeSet 1635406_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Pkg21D. Gene sequence location is 2L:786153..790798.