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This gene article is a stub. It has been seeded with the automatically generated summary from FlyBase release FB2013_02. Please help improve this summary by logging in and editing it.

To return to FlyBase, see FlyBase Gene Report: Dmel\Prp8.

Symbol Dmel\Prp8
Name pre-mRNA processing factor 8
Species Drosophila melanogaster
Annotation symbol CG8877
FlyBase ID FBgn0033688

The gene pre-mRNA processing factor 8 is referred to in FlyBase by the symbol Dmel\Prp8 (CG8877, FBgn0033688). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: mRNA splicing, via spliceosome; neurogenesis. 7 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: JAB1/Mov34/MPN/PAD-1; PRO, C-terminal; PROCN; PRP8 domain IV core; Pre-mRNA-processing-splicing factor 8; Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding; Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding; RNA recognition motif, spliceosomal PrP8. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640679_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Prp8. Gene sequence location is 2R:8041763..8050503.


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