To return to FlyBase, see FlyBase Gene Report: Dmel\RfC3.
|Name||Replication factor C subunit 3|
The gene Replication factor C subunit 3 is referred to in FlyBase by the symbol Dmel\RfC3 (CG5313, FBgn0032244). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: DNA binding. There is experimental evidence that it is involved in the biological process: lateral inhibition; neurogenesis. 3 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; chaeta. It has one annotated transcript and one annotated polypeptide. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, core; DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal; Replication factor C, C-terminal domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1637166_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of RfC3. Gene sequence location is 2L:10419190..10420612.