To return to FlyBase, see FlyBase Gene Report: Dmel\Tdc2.
|Name||Tyrosine decarboxylase 2|
The gene Tyrosine decarboxylase 2 is referred to in FlyBase by the symbol Dmel\Tdc2 (CG30446, FBgn0050446). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: tyrosine decarboxylase activity; aromatic-L-amino-acid decarboxylase activity. There is experimental evidence that it is involved in the biological process: locomotory behavior; oviposition; behavioral response to cocaine. 5 alleles are reported. The phenotypes of these alleles are annotated with: type II bouton; multidendritic neuron; adult brain. It has one annotated transcript and one annotated polypeptide. Protein features are: Aromatic-L-amino-acid decarboxylase; Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal-phosphate binding site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1632764_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Tdc2. Gene sequence location is 2R:2572250..2577479.